Aug 4 2026

george

Letter to STH: AI Models for Viscoelastic Assays

Click here for a summary of a letter to the STH editor: Yeong JK, Panigada M, Altememi MA, Favaloro EJ, Fan BE. Large language models for viscoelastic tests: a head-to-head evaluation of ChatGPT, Gemini, and DeepSeek for thromboelastography and ROTEM interpretation. Semin Thromb Hemost. 2026. doi: 10.1055/a-2918-4009. PMID: 42520817. In addition, click here for a […]

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Global Hemostasis Assays

May 15 2026

george

Clot Waveform Analysis

Click here for this open-access article on waveform analysis and for access to Seminars in Thrombosis and Hemostasis Issue 4, 2026: Tan JY, Raden M, De Guzman T, Wong WH. Decoding clot waveform analysis: toward better understanding and harmonization. Semin Thromb Hemost 2026; 52(04): 460-475 DOI: 10.1055/a-2778-9810. Abstract Clot waveform analysis (CWA) extends routine coagulation […]

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Global Hemostasis Assays

Mar 4 2026

george

Review: AI in Thrombosis and Hemostasis

Click here for this open-access article that describes AI in thrombosis and hemostasis. (This is the first time we’ve posted about AI). Altememi MA, Favaloro EJ, Islam MZ, Santhakumar AB. Artificial intelligence and machine learning in thrombosis and hemostasis: a scoping review of clinical and laboratory applications, challenges, and future directions. Clin Chem Lab Med. […]

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Global Hemostasis Assays

Feb 22 2026

george

JTH Editorial: The Problem With Coagulopathy…

Click here for the open-access editorial Thachil J. The problem with coagulopathy …. J Thromb Haemost. 2022;20:2171-2172. doi: 10.1111/jth.15795. PMID: 35733290. Abstract Coagulopathy is inextricably linked to the field of hemostasis and thrombosis. In the same manner, hemostasis and thrombosis may deal with bleeding and clot formation; coagulopathy also may be connected to bleeding or […]

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Global Hemostasis Assays

Feb 19 2026

george

CAP Today: Hemostasis Testing While on DOACs

This open-access January 26 CAP Today document features the opinions of several experts as they address the limitations of coagulation testing in patients taking DOACs, such as dabigatran, rivaroxaban, or apixaban, and speculates on the coagulation effects of the upcoming anti-XI antithrombotics: Direct Oral Anticoagulants–New Guidance, Lab Testing.

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Anticoagulant Therapy

Feb 6 2026

george

Review: Hemostasis Biomarkers

Here is a January 2026 comprehensive review of commonly used and esoteric hemostasis disorder biomarkers in downloadable format: Reardon B, Pasalic L, Favaloro EJ. Biomarkers of coagulation disorders—where to from here? Biomolecules 2026: 16, 235. https://doi.org/10.3390/biom16020235. Abstract Disorders of thrombosis and bleeding contribute to a significant morbidity and mortality burden worldwide. Correctly identifying contributing factors […]

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Global Hemostasis Assays

Feb 4 2026

george

Review: Clot Waveform Analysis

Click this open-access article that reviews attempts at harmonization of clot waveform analysis: Tan JY, De Guzman MRT, Wong WH, et al. Decoding clot waveform analysis: toward better understanding and harmonization. Semin Thromb Hemost. 2026. doi: 10.1055/a-2778-9810. PMID: 41506647. Abstract Clot waveform analysis (CWA) extends routine coagulation assays (activated partial thromboplastin time [PTT] and prothrombin […]

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Screening Assays

Oct 29 2025

george

PT and PTT Illustrated Mechanisms

For an illustrated overview of the hemostasis mechanisms associated with the PT and PTT, obtain this article from your medical library: Harris NS, Marin MJ, Butenas S. Beyond prothrombin time and activated partial thromboplastin time: coagulation in vivo-an illustrated review. Lab Med. 2025;56:438–47. doi: 10.1093/labmed/lmae125. PMID: 40319459. Abstract The steps that initiate coagulation in vivo […]

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Coagulation Factors

Sep 17 2025

george

Effect of Rebalancing Therapy on Coagulation Assays

Click to read this open-access article that explores the effects of antithrombin reduction (rebalancing) hemophilia therapy on a series of coagulation tests: Chhabra, ES ; Liu, M. Evaluation of the interference of fitusiran and antithrombin lowering in plasma on routine coagulation assays. Research and practice in thrombosis and haemostasis, 2025;9:102989–9.

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Bleeding Disorders

Sep 12 2025

george

Cell-based Coagulation Overview

Check your medical library to read Harris NS, Marin MJ, Butenas S. Beyond prothrombin time and activated partial thromboplastin time: coagulation in vivo-an illustrated review. Lab Med. 2025;56:438–47. doi: 10.1093/labmed/lmae125. PMID: 40319459. Here’s the abstract: The steps that initiate coagulation in vivo are different from the components of prothrombin time (PT) and activated partial thromboplastin time […]

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Coagulation Factors