Global Hemostasis Assays

Hemosonics Quantra QStat Cartridge

On November 30, Hemosonics, LLC announced that they had received 510(k) market clearance from the U.S. Food and Drug Administration (FDA) for the Quantra Hemostasis System with QStat cartridge, which accompanies their QPlus cartridge. Click here for the press release.

Viscoelastometry

November, 2022 Quick Question: PT/INR

The stem or our November 2022 Quick question asked, If you use the PT when no warfarin is being measured, how do you report the results? Our 51 participants responded as follows: Report both PT and INR: 34 [66%] Report PT/MRI ratio: 0 Report PT only: 14 [27%] Report INR only: 4 [7%] Answer 2 […]

Anticoagulant Therapy

November, 2022 Quick Question

Please visit and respond to our November 2022 Quick Question, submitted by Dave McGlasson. The question asks, "If you use the PT when no warfarin is being measured, how do you

June, 2022 Quick Question Summary: VET Instruments

Our June 2022 Quick Question asked, “What viscoelastometry [VET] equipment is employed in your ER or OR?” Out total response was 22 participants. Answers: Thromboelastograph 5000 [TEG]: 18% [4] Thromboelastograph 6S [TEG]: 18% [4] Thromboelastometry [ROTEM]: 23% [5] Quantra Qplus: 0 Sienco Sonoclot: 0 Our lab doesn’t manage VET testing: 41% [9] At the June […]

Global Hemostasis Assays

OR Hemostasis Presentation

I [Geo] will present “Hemostasis in the Operating Room” at the American Society for Clinical Laboratory Sciences Joint Annual Meeting in Grand Rapids, Michigan, Wednesday, tomorrow, June 29, 1:45–2:45 EDT. The “JAM” will be a hybrid meeting, so presentations will be available on-site or online. My talk covers anticoagulation and coagulopathy management and features the […]

Global Hemostasis Assays

ASCLS Annual Meeting June 26–30

The ASCLS, AGT, and SAFMLS hybrid annual meeting [JAM] is planned for June 26–30, 2022 in Grand Rapids, MI. Click here for the details. George presents Operating Room Hemostasis Testing Wednesday, June 29, in-person 1:45–2:45 ET. The talk includes how the OR employs the activated clotting time or viscoelastometry to monitor heparin superdosing and reversal. […]

September 2021 Quick Question: TEG

Our September 2021 Quick Question attracted only 14 responses, perhaps reflecting the minimal communication between the central laboratory and the anesthesiology service in most operating rooms. Our question was “What is the favorite near-patient viscoelastic test of US anesthesiologists?” Here are your answers: Rotational thromboelastometry [ROTEM]: 14% [2] Resonance sonorheometry [Quantra]: 7% [1] Activated clotting […]

Global Hemostasis Assays

Dilute Thrombin Time

From Deanna Miller, Children’s Hospital of Alabama. Do you have any good references for diluted thrombin and utilization of this test? What dilution is best? 1:1 or 1:3? Hello, Deanna, and thank you for your question. We use the plasma-diluted thrombin time to measure the direct thrombin inhibitors [DTIs] dabigatran, argatroban, or bivalirudin. The assay […]

Anticoagulant Therapy

Covid-Coag Conversation 9-15-20

You are invited to our Tuesday, September 15, 2020 webinar, Covid-Associated Coagulopathy: A Conversation about the Controversies and Confusion featuring pathology expert Andrew J. Goodwin, MD, University of Vermont Medical Center Laboratory Director. Click https://conta.cc/3aMDoNp for the eblast or bit.ly/COVID-Coag to go directly to the registration page. Covid-Coag is a PACE-accredited one-hour presentation, 5–6 PM […]

Arterial Thrombosis

Effect of Fibrinogen on PT and PTT

From Alan Neal, Pathlab, NZ. Just wanted a private conversation about the January 11, 2018 Fritsma Factor entry, “POC and Plasma-Based PT/INRs.” I do not agree with the comments made within this article and challenge the logic used. Essentially, if monitoring an enzymatic pathway such as coagulation, with the ‘detector’ being used is fibrinogen to […]

Global Hemostasis Assays

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George Fritsma is a medical laboratory scientist, educator, and author. George holds faculty appointments with Rutgers University and Michigan State University, and is a member of the International Society on Thrombosis and Hemostasis, American Association of Clinical Chemists, and American Society for Clinical Laboratory Science.

Cheat Sheets from George

Quick Question