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Platelet Function Testing

July 2022 QQ: Reduced concentration RIPA test.

Our July 2022 Quick Question asks, “What von Willebrand disease [VWD] subtype is identified using the reduced concentration ristocetin-induced platelet aggregometry [RIPA] test?” Many of the VWD types and subtypes are currently identified using molecular diagnosis, however, the “legacy” phenotypic tests often provide a speedy and inexpensive shortcut. This may be one such case. Please […]
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VITT Mechanism Nature Preview

Here is a research article that was rushed to print in the July 7, 2021 Nature that describes the precise pathophysiology of vaccine-induced immune thrombotic thrombocytopenia [VITT]. VITT is the critical 1/60,000 incidence adverse event associated with the adenoviral vector employed in the Astra-Zeneca and Johnson and Johnson vaccines, among others. VITT resembles heparin-induced thrombocytopenia […]
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