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Platelet Function Testing

Nov 2 2026
george

Platelets in Children

Check with your local medical library for this review on pediatric platelet development: Letunica N, Monagle P, Attard C. Platelets in children: physiological function, developmental regulation, and clinical significance in disease states. Semin Thromb Hemost. 2026. doi: 10.1055/a-2907-8906. PMID: 42442705. Abstract Platelets play a fundamental role in hemostasis; however, their phenotype, reactivity, and function vary […]
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Platelet Function Testing
Aug 4 2026
george

Review: AI Designing the Future of Hemostasis

Check your medical library for this review article on AI-based peptide design to modify the GPIbα-VWF interaction in platelet-type von Willebrand disease: Kazmirchuk TDD, Wang J, Corbette J, et al. Designing the future of hemostasis. Semin Thromb Hemost. 2026 Jun 9. doi: 10.1055/a-2885-4368. PMID: 42225137. Abstract Bleeding disorders arising from dysfunctional platelet-protein interactions pose a […]
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Bleeding Disorders
Apr 25 2026
george

Platelet-inflammation Interactions

Click here for a provocative open-access article describing the now established relationship between platelets and inflammatory processes: Escaig R, Kreutz L, Kaiser R, Nicolai L. Platelet effector functions in inflammation. Res Pract Thromb Haemost. 2026;10:103412. doi: 10.1016/j.rpth.2026.103412. PMID: 42027308; PMCID: PMC13100282. Abstract A State of the Art lecture titled “Platelet effector functions in inflammation” was […]
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Platelet Function Testing
Mar 11 2026
george

Effects of Platelet Transfusions on Neonates

Check your medical library for this article that describes levels of morbidity and mortality of neonates receiving platelet transfusions:  Davenport P, Feldman HA, Young V, et al. Effects of platelet transfusions on neonatal bleeding and inflammation. Pediatr Res. 2025 Nov 5. doi: 10.1038/s41390-025-04498-9. Erratum in: Pediatr Res. 2025 Dec 2. doi: 10.1038/s41390-025-04676-9. PMID: 41193819. Abstract […]
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Bleeding Disorders
Feb 6 2026
george

Review: Hemostasis Biomarkers

Here is a January 2026 comprehensive review of commonly used and esoteric hemostasis disorder biomarkers in downloadable format: Reardon B, Pasalic L, Favaloro EJ. Biomarkers of coagulation disorders—where to from here? Biomolecules 2026: 16, 235. https://doi.org/10.3390/biom16020235. Abstract Disorders of thrombosis and bleeding contribute to a significant morbidity and mortality burden worldwide. Correctly identifying contributing factors […]
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Global Hemostasis Assays
Jan 23 2026
george

Diagnostic Equity: PB Platelets in Myelofibrosis

This question appeared on the Diagnostic Equity website on 1-21-2026: “How well do peripheral blood platelet findings correlate with bone marrow fibrosis or megakaryocyte abnormalities in myelofibrosis, and when do lab results suggest a marrow reassessment might be useful?” Diagnostic Equity expert Ryan J. Tom, MS, MLS(ASCP)CM (DCLS Resident) offered this answer: Platelet findings can […]
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Platelet Function Testing
Dec 12 2025
george

Platelet Function Preservation Following Cell Salvage

Thanks to colleague Dave McGlasson, MS, MLS for identifying this open-access original research study that describes the effects of intraoperative cell salvage on platelet function. Blum LV, Sertdere F, Iken S, et al. Preservation of platelet function after intraoperative cell salvage using the i-SEP same device in cardiac surgery. J Cardiothorac Vasc Anesth. 2025:S1053-0770(25)01058-4. doi: […]
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Platelet Function Testing
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George Fritsma MS MLS

George Fritsma is a medical laboratory scientist, educator, and author. George  is a member of the International Society on Thrombosis and Hemostasis, the International Society for Laboratory Hematology, and the American Society for Clinical Laboratory Science.

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