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How to Measure Plasma Efanesoctocog Alfa [Altuviiio]

For those like me [Geo] who are just learning of it, efanesoctocog alfa (“EFA,” ALTUVIIIO™), US FDA-approved in February of 2023 is Sanofi/Sodi’s extended half-life synthetic FVIII concentrate whose FVIII molecule is fused to a VWF fragment, thus extending the half-life to ~52 hours, requiring once-a-week infusions. Here is the FDA statement: Efanesoctocog alfa (ALTUVIIIOTM; […]
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Hemostasis in Selected Populations

In Keohane EM, Otto CN, Walenga JM: Rodak’s Hematology; Clinical Principles and Applications, Sixth Edition, 2020, Dr. Linda Goossen provides a timely and clinically significant chapter, “Hematology and Hemostasis in the Pediatric, Geriatric, and Pregnant Populations.’ Owing to next-generation sequencing, the In-Vitro Diagnostics world continues to partition reference intervals, therapeutic target ranges, and treatments to […]
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