What is Fibrinogen Longmont?

Click here for an open-access case report of a variant fibrinogen: Ma C, Li X, Yin D, et al. Rapid laboratory identification of fibrinogen Longmont: a case report and literature review. Front Med (Lausanne). 2026;13:1781076. doi: 10.3389/fmed.2026.1781076. PMID: 42440479; PMCID: PMC13333428. Abstract This study reports a case of a patient with unstable angina with abnormally […]

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Bleeding Disorders

Oct 10 2026

george

Illustrated Review: Acquired Hemophilia A

Here is a richly illustrated review of acquired hemophilia A: Guillet B, d’Oiron R, Lacroix-Desmazes S, et al. Acquired hemophilia A: an illustrated review based on the French National Guidelines. Res Pract Thromb Haemost. 2026;10(5):106820. doi: 10.1016/j.rpth.2026.106820. PMID: 42657325; PMCID: PMC13508639. Abstract Acquired hemophilia A is a rare but potentially life-threatening autoimmune bleeding disorder caused […]

Bleeding Disorders

Transfusion Journal Case Series: Inherited FX Deficiency

Here is an open-access review of inherited FX disorders: Chitlur M, Amos LE, Reding MT, Sabo C, Acharya SS. Characterization and management of patients with hereditary factor X deficiency: A case series. Transfusion. 2025;65(10):1786-1792. doi: 10.1111/trf.18377. PMID: 41104456; PMCID: PMC12531909. Abstract Background: Hereditary factor X deficiency (HFXD) is an ultra-rare, autosomal recessive bleeding disorder that […]

Bleeding Disorders

Review: Inherited Bleeding Disorder in Women

Select this open-access review of inherited bleeding disorders in women: Connell NT, Davies J, Abdul-Kadir R, Kaplan Z. Obstetric and gynaecologic considerations in inherited bleeding disorders. Haemophilia. 2026. doi: 10.1111/hae.70267. PMID: 41988968. Abstract Women and girls with inherited bleeding disorders (IBD) face distinct gynaecologic and obstetric challenges, largely due to increased bleeding risk during key […]

Bleeding Disorders

STH Review: Hemostasis and Menstrual Bleeding

This year’s World Thrombosis Day focuses on hemostasis issues in women. Select this open-access Seminars review: Dodart R, Ku DN. What stops menstrual bleeding? Hemostatic mechanisms in the menstruating endometrium. Semin Thromb Hemost. 2026. doi: 10.1055/a-2967-9335. PMID: 42843808. Abstract Menstrual bleeding is one of the most common physiological bleeding events in humans, yet the mechanisms […]

Bleeding Disorders

A Summary of VWD Management by Dr. Favaloro

See this open-access editorial summarizing current VWD diagnosis and management. Favaloro EJ. 100 years of von Willebrand disease: celebrating a significant milestone in von Willebrand disease diagnostics and management. Semin Thromb Hemost. 2026;52(7):762-764. doi: 10.1055/a-2877-9583. PMID: 42190737. Further, here’s a link to the entire Seminars in Thrombosis and Hemostasis, October 2026, that addresses Hemostasis in […]

Bleeding Disorders

Women and Girls With Hemophilia and Hemophilia Carriers

This open-access article details ISTH guidance in managing hemophilia in women and girls: Srivaths L, Ardila J, Fijnvandraat K, van Galen K, James P, Larson J, Shapiro S, Sidonio R, Escobar M. The diagnosis and evaluation of women and girls with hemophilia and hemophilia carriers: guidance from the SSC of the ISTH. J Thromb Haemost. […]

Bleeding Disorders

Study Results: Novel Thrombin Generation Assay Monitors Emicizumab and Octocog Alfa

Here are the open-access results of a study testing the efficacy of a novel intrinsic trigger reagent (platelet-poor plasma [PPP] Reagent INT) for monitoring emicizumab and octocog alfa: Urlings EH, Heubel-Moenen FCJI, van Oerle R, et al. Intrinsic activated thrombin generation for treatment efficacy and monitoring of octocog alfa and emicizumab in severe hemophilia A. […]

Bleeding Disorders

A Haematologica Review of all Hemophilia Rebalancing Therapy Efforts

Here is an open-access article describing all efforts to develop effective rebalancing therapy, including Latarcibart®, a MOAB that suppresses PS, not previously described in FF: Van Thillo Q, Hermans C. Rebalancing agents in hemophilia: knowns, unknowns, and uncertainties. Haematologica. 2025 Dec 1;110(12):2902-2912. doi: 10.3324/haematol.2025.288245. PMID: 40820726; PMCID: PMC12666285. Abstract Treatment options for patients with hemophilia […]

Bleeding Disorders

Monitoring ADAMTS13 Deficiency: An Expert Rev. Hematology Review

Here is a current open-access article about ADAMTS13 deficiency: Binder NB, Depasse F, Spannagl M, et al. Clinical laboratory diagnostics and monitoring of ADAMTS13 deficiency and of related diseases: an integrated approach. Expert Rev Hematol. 2026 Sep;19(9):1037-1057. doi: 10.1080/17474086.2026.2702550. PMID: 42461718. Abstract Introduction: ADAMTS13, a crucial enzyme in hemostasis that specifically cleaves von Willebrand factor […]

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Bleeding Disorders

Bleeding Disorders

What is Fibrinogen Longmont?

Illustrated Review: Acquired Hemophilia A

Transfusion Journal Case Series: Inherited FX Deficiency

Review: Inherited Bleeding Disorder in Women

STH Review: Hemostasis and Menstrual Bleeding

A Summary of VWD Management by Dr. Favaloro

Women and Girls With Hemophilia and Hemophilia Carriers

Study Results: Novel Thrombin Generation Assay Monitors Emicizumab and Octocog Alfa

A Haematologica Review of all Hemophilia Rebalancing Therapy Efforts

Monitoring ADAMTS13 Deficiency: An Expert Rev. Hematology Review

George Fritsma MS MLS

Cheat Sheets from George

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