Bleeding Disorders

Hemophilia A Patient Satisfaction With Extended Half-life Altuviiio® Therapy

Click here for an open-access post hoc study report on patient satisfaction with once-weekly Altuviiio® (Efanesoctocog alfa) therapy: Spasov E, Quon D, Fukutake K, et al. Treatment satisfaction and patient preference for efanesoctocog alfa over previous hemophilia A treatment: Results from the XTEND-1 phase 3 clinical trial. Curr Ther Res Clin Exp. 2026;105:100839. doi: 10.1016/j.curtheres.2026.100839. […]

Bleeding Disorders

Type 2M VWD

A LinkedIn note by Shadi Tabibian, 2nd. Laboratory Hematologist and Director, Iranian Comprehensive Hemophilia Care Center; Deputy of Research, Blood Diseases Research Center, Iran University of Medical Sciences: Can a “normal” VWF activity-to-antigen ratio rule out Type 2 von Willebrand disease? Not always. One of the most interesting diagnostic lessons from this recent review is the […]

Bleeding Disorders

A Coag Conversation: 100 Years of VWD and Upcoming Advances: Conversation 3

On August 11, 2026, we posted the third and concluding conversation of “100 Years of Von Willebrand Disease and Upcoming Advances” with Robert F. Sidonio, Jr., MD, MSc. Click here for #3: Advanced Assays and von Willebrand Disease Management.

Bleeding Disorders

Effect of PCC on Bleeding Patients with FXa Inhibitor

Click here for a current study report on PCC therapy in patients with FXa inhibitors who are bleeding or needing surgery: Shaw JR, Gray H, Xu Y, et al. Effect of PCC on thrombin generation in patients on FXaI with bleeding or needing urgent surgery (GAUGE). Blood Adv. 2026;10(15):5378–88. doi: 10.1182/bloodadvances.2026020203. PMID: 42275536; PMCID: PMC13452292. […]

Bleeding Disorders

Events and Conferences: Bleeding Disorders Conference August 13–15

Thanks to Elaine Benoit, PBI’s marketing guru, for recent updates to our Events and Conferences Calendar. This week is the NBDF’s Bleeding Disorders Conference in Orlando, FL, USA, August 13–15. It’s not too late to register. Our colleagues at George King Bio-Medical will exhibit at booth 100. If you don’t see your hemostasis-related event or […]

Review: AI Designing the Future of Hemostasis

Check your medical library for this review article on AI-based peptide design to modify the GPIbα-VWF interaction in platelet-type von Willebrand disease: Kazmirchuk TDD, Wang J, Corbette J, et al. Designing the future of hemostasis. Semin Thromb Hemost. 2026 Jun 9. doi: 10.1055/a-2885-4368. PMID: 42225137. Abstract Bleeding disorders arising from dysfunctional platelet-protein interactions pose a […]

Bleeding Disorders

July 2026 QQ Summary: VWD Therapeutic

Our July 2026 QQ asked: What VWD therapeutic is NOT a replacement factor? Our 24 participants responded… Desmopressin: 18 (75%) Humate P: 1 (4%) Vonvendi: 4 (17%) Wilate: 1 (4%) VWD bleeding is first managed by applying “PRICE:” protection, rest, ice, compression, and elevation. Next, desmopressin (DDAVP) is administered via injection, infusion, and, in Europe, […]

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Emicizumab Therapy for the Newborn

Click for this Hemostasis Today column, Abdul Mannan: HAVEN 7 and the Future of Early Haemophilia Care. For a detailed follow-up to the HAVEN 7 trial, check your medical library for de Kovel M, Kenet G, Motwani J, et al; PedNet Study group. FVIII exposure, bleeding outcomes, and inhibitor development in 80 PUPs and MTPs […]

Bleeding Disorders

Why Does Blood Group O Reduce VWF?

Dr. Abdul Mannan’s LinkedIn post, “Why Does Blood Group O Reduce VWF?” presents the physiology of VWF in blood group O.

Bleeding Disorders

Why Clotting Patients Bleed

Abdul Mannan, Consultant Haematologist at Betsi Cadwaladr University Health Board, shared a column, Why Clotting Patients Bleed, in Hemostasis Today.

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George Fritsma is a medical laboratory scientist, educator, and author. George is a member of the International Society on Thrombosis and Hemostasis, the International Society for Laboratory Hematology, and the American Society for Clinical Laboratory Science.

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