COVID

“Covid Coag”

On May 26, I (Geo) posted a link to our informational module, The Cell-based Coagulation Model. On May 15, I posted a link to our Coagulation Overview Module. The third in a series of “Mechanism” modules, and perhaps the most complex, is entitled Covid Coag. Though thanks to vaccination technology, we think less today about […]

Bleeding Disorders

Letter to 2024 NEJM Links Adenoviral Anti-PF4 to VITT

Click here for the full news release from Flinders University News: New research, led by Flinders University and international experts, has finally uncovered how a rare blood-clotting condition can occur after some COVID-19 adenovirus-based vaccines or after a natural adenovirus infection. First paragraph: To the Editor: Disorders caused by antibodies against platelet factor 4 (PF4) gained […]

Arterial Thrombosis

What is PITT?

Click below for an open-access article that classifies VITT and HIT as members of a platelet factor 4 (PF4) disorder, anti-PF4 mediated thrombocytopenia and thrombosis (PITT). Nicolson PLR, Montague SJ, Buka RJ, et al. Anti-PF4 mediated thrombocytopenia and thrombosis associated with acute cytomegalovirus infection displays both HIT-like and VITT-like characteristics. Br J Haematol. 2025. doi: […]

Arterial Thrombosis

COVID-Coag Information

Early in 2021 Fritsma Factor published a narrated 40-minute PowerPoint file named COVID-Coag. While it may seem dated, the presentation links the SARS-Cov19 virus to acute inflammation, platelet activation, DIC, SIC, TMA, TTP, and VITT (recently categorized as “PITT“), insights born of our intense studies of the pandemic. Further, this article appears in the April […]

Readily Measurable Products of SARS-Cov-2 Endothelial Cell Injury

This is the second in a series of discussions about the relationship between hemostasis and inflammation. These discussions were part of our Rutgers CLSC 5124 Advanced Hemostasis course that features answers provided by our participants. List the readily measurable products of SARS-Cov-2 mediated endothelial cell injury. SARS-CoV-2 is increasingly being recognized as a disease of […]

Coag Conversation Part 3: VWF and ADAMTS13: Cardiovascular Diseases

Introducing The Many Faces of von Willebrand Factor or, von Willebrand Factor, ADAMTS13, Malignancy and Beyond Part 3: von Willebrand Factor and ADAMTS13; Thrombotic Mechanisms and Cardiovascular Diseases. This 30″ talk features George A. Fritsma, MS, MLS, proprietor of The Fritsma Factor, Your Interactive Hemostasis Resource, and Emmanual Favaloro, PhD, Principal Hospital Scientist at the […]

Arterial Thrombosis

New Educational Module: TMAs

Announcing our 35-minute educational module, Thrombotic Microangiopathies, or TMAs, also known as TTP, STEC-HUS, aHUS, ADAMTS13, VWF, MAHA, TMA, PLEX, and HELLP, what does it all mean? We hope you will find this helpful.

Bleeding Disorders

Covid Lab Table

Clickor tap here for a current table of Covid lab values.

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George Fritsma is a medical laboratory scientist, educator, and author. George is a member of the International Society on Thrombosis and Hemostasis, the International Society for Laboratory Hematology, and the American Society for Clinical Laboratory Science.

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