Register Login

Anticoagulant Therapy

Aug 17 2026
george

Simplified DOAC–Stop Proof of Concept

Click here for this 2024 open-access article describing the use of DOAC-Stop®: Exner T, Dangol M, Favaloro EJ. Simplified method for removing direct oral anticoagulant interference in mechanical coagulation test systems–a proof of concept. J Clin Med. 2024;13:1042. doi: 10.3390/jcm13041042. PMID: 38398355; PMCID: PMC10889288. Abstract Background: Direct oral anticoagulants (DOACs) cause unwanted interference in various […]
read more
Comments (0)
Anticoagulant Therapy
Jul 14 2026
george

Review: Laboratory Monitoring and Measuring of Clinical Anticoagulants

Check your medical library for this July, 2026 review: Favaloro EJ, Reardon B, Pasalic L. Laboratory monitoring and measuring of clinical anticoagulants. Semin Thromb Hemost. 2026. doi: 10.1055/a-2907-8841. PMID: 42442704. Abstract Haemostasis reflects a balance between procoagulant and anticoagulant forces. A relative excess of procoagulant forces and/or a relative lack of anticoagulant forces can predispose […]
read more
Comments (0)
Anticoagulant Therapy
Jul 13 2026
george

A LAC Assay that Resists DOAC Interference

Click Rahman M, Black KM, Sadeghi-Khomami A; An Automated Lupus Anticoagulant Assay Resistant to Anticoagulant Drugs Including DOACs and Oral FXI Inhibitors for a 2016 ISTH poster that documents an updated LAC assay. Background Direct oral anticoagulants (DOACs) and oral FXI inhibitors interfere with LAC testing by prolonging clotting times and increasing assay variability. Activated charcoal […]
read more
Comments (0)
Anticoagulant Therapy
Jul 6 2026
george

External Quality Assessment for Anti-FXa LMWH Assays

Check with your local medical library for this thought-provoking article: Favaloro EJ, Arunachalam S, Pasalic L. External quality assessment for low molecular weight heparin monitoring in the Australasia/Asia-Pacific region. Semin Thromb Hemost. 2026. doi: 10.1055/a-2900-7026. Epub ahead of print. PMID: 42398957. Abstract LMWH remains a widely used parenteral anticoagulant in hospital and outpatient settings for […]
read more
Comments (0)
Anticoagulant Therapy
Jul 4 2026
george

Are we Overusing LMWH?

A provocative open-access article posted on LinkedIn by Dr. Emmanuel Favaloro suggesting we are overusing LMWH: Gurumurthy G, Fan B, Gurumurthy J, et al. Should we focus on sustainable thromboprophylaxis and avoid overuse of low-molecular-weight heparins? Research and Practice in Thrombosis and Haemostasis, 2026; 10. DOI: 10.1016/j.rpth.2026.106794. Abstract Low-molecular-weight heparins (LMWHs) have become a near-routine prescription […]
read more
Comments (0)
Anticoagulant Therapy
May 15 2026
george

Perioperative Management of Antiphospholipid Syndrome Study

Click here for the open-access article, Paquette M, Miranda S, Xu Y, et al. Perioperative management of antithrombotic therapy in patients with thrombotic antiphospholipid syndrome. Blood Adv. 2026;10(9):3218–28. doi: 10.1182/bloodadvances.2026019610. PMID: 41843780; PMCID: PMC13136740. Abstract Patients with thrombotic antiphospholipid syndrome (APS) frequently require interruption of anticoagulation for invasive procedures; however, data to guide the perioperative […]
read more
Comments (0)
Anticoagulant Therapy
Load more

George Fritsma MS MLS

George Fritsma is a medical laboratory scientist, educator, and author. George  is a member of the International Society on Thrombosis and Hemostasis, the International Society for Laboratory Hematology, and the American Society for Clinical Laboratory Science.

read more

Cheat Sheets from George

Name

Questions or Comments?

Email George

Quick Question

Which is NOT an endogenous coag control protein?