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High-sensitivity D-dimer?

A colleague has seen references to a “High-sensitivity” D-dimer assay. George answered he’s not heard of this, perhaps it is just a synonym for a standard D-dimer assay. If you have any experience with this, please respond to [email protected] or comment below.

Comments (3)
Dec 18, 2019 11:48am

The high sensitive DDIMER
The high sensitive D-dimwe that I was exposed to is the ELISA method by an instrument called VIDAS. This is the gold standard method compared to latex method by manual or automated. Rodel

Dec 16, 2019 2:44pm

My understanding is that all
My understanding is that all automated / immunoturbidimetric and POC D-dimer assays are considered “high sensitivity.” The “high sensitivity” terminology is used to distinguish quantitative D-dimer assays from whole blood and/or qualitative card assays which had been used before the advent of the automated and POC assays. See Di Nisio M et al. Diagnostic accuracy of D-dimer test for exclusion of VTE: a systematic review. JTH 2006;5:296-304.

Oct 2, 2019 11:49pm

Hi , in general terms the
Hi , in general terms, manufacturers use this term to promote their version of D-dimer having a higher sensitivity for VTE/PE prediction. The automated lab based LIA versions compared to the POC versions with lower sensitivity. Robyn

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