Sep 27 2019
A colleague has seen references to a “High-sensitivity” D-dimer assay. George answered he’s not heard of this, perhaps it is just a synonym for a standard D-dimer assay. If you have any experience with this, please respond to [email protected] or comment below.
The high sensitive DDIMER
The high sensitive D-dimwe that I was exposed to is the ELISA method by an instrument called VIDAS. This is the gold standard method compared to latex method by manual or automated. Rodel
My understanding is that all
My understanding is that all automated / immunoturbidimetric and POC D-dimer assays are considered “high sensitivity.” The “high sensitivity” terminology is used to distinguish quantitative D-dimer assays from whole blood and/or qualitative card assays which had been used before the advent of the automated and POC assays. See Di Nisio M et al. Diagnostic accuracy of D-dimer test for exclusion of VTE: a systematic review. JTH 2006;5:296-304.
Hi , in general terms the
Hi , in general terms, manufacturers use this term to promote their version of D-dimer having a higher sensitivity for VTE/PE prediction. The automated lab based LIA versions compared to the POC versions with lower sensitivity. Robyn