Cold Agglutinins and Clotting

Another good one from Kim Kinney at Clarian:

Hi George,

I have a question regarding cold agglutinins and clotting coag samples.  I have heard from one of our sites that specimens from someone with a cold agglutinin will clot in citrate tubes. In order to get a good sample the tubes and the blood must be heated to 37 degrees…I have not heard of this.  Any opinions out there??

(Kim, I assume this means the blood is collected and maintained at 37 degrees until separation, right?) Geo