Webinar Recording: VWF: Friend or Foe

A recording of our January 26, 2021 webinar, von Willebrand Factor, Friend or Foe [click] is now available on the BioMedica Diagnotics, Inc. home page. Here is a summary from our January announcements: Von Willebrand factor [VWF] is crucial to platelet adhesion and proper effective coagulation. In addition, VWF appears to be associated with inflammation […]

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Events

Jan 31 2021

george

Jan, 2021 QQ: CFX Answers

Our January, 2021 Quick Question asked, “How does your facility monitor warfarin in an atrial fibrillation [AFIB] patient with lupus anticoagulant [LAC]? The answers were… PT–INR; it is valid in LAC [33%] Chromogenic factor X [10, CFX] [33%] Chromogenic anti-factor Xa [23%] None: we switch to a DOAC [11%] Our question attracted too small a […]

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Anticoagulant Therapy

Jan 11 2021

george

New: CRYOcheck Hex LA

Congratulations to Precision BioLogic Inc. who today announce the release of their newly developed CRYOcheck HexLA® [click]. Following several years in development, CRYOcheck HexLA is FDA cleared, CE Marked, Health Canada authorized and ncluded on the Australian Register of Therapeutic Goods (ARTG). Thanks to PBI’d Elaine Benoit for the heads-up.

Thrombophilia

Jan, 2021 QQ: The Chromogenic Factor X Assay

Before 2010, several articles were published supporting the chromogenic factor X [CFX] assay [not to be confused with the chromogenic anti-factor Xa heparin assay] for monitoring warfarin therapy, especially in patients whose lupus anticoagulant [LAC} could falsely prolong the prothrombin time. Two of these articles are attached below. While the data published made it clear […]

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Anticoagulant Therapy

Dec 21 2020

george

CLS Journal Hemostasis Articles

A recent 2020 Clinical Laboratory Science Journal, publication of the American Society for Clinical Laboratory Science, offers the following hemostasis-related articles, purchasable for $5 each: Nardi MA. Emicizumab and the clinical laboratory. DOI: https://doi.org/10.29074/ascls.119.002204 Ketelson B. Molecular action of ADAMTS13 and transfusion therapies of thrombotic thrombocytopenia pupura. DOI: https://doi.org/10.29074/ascls.120.002287 Ketelson B. An overview of the […]

Bleeding Disorders

DOAC-STOP In Vitro DOAC Removal and LAC

From Asha Rajai: Is it OK to use DOAC-STOP for lupus testing? Has it been approved by ISTH or CLSI? Hello, Asha. Yes, DOAC-STOP [DiaPharma] and DOAC-Remove [Aniara] effectively absorb dabigatran, rivaroxaban, or apixaban from specimens that are submitted for lupus anticoagulant [LAC] testing, allowing for accurate PTT– and DRVVT-based screen and confirm assays for […]

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Anticoagulant Therapy

Nov 3 2020

george

LAC Testing on Warfarin Specimens

A colleatue writes that we frequently encounter cases in which the physician orders a lupus anticoagulant [LC] profile despite a normal PTT. We use Siemens ACTIN FSL and it returns a positive. Of course with a normal PTT, there is no place for mixing study. How to explain this? Also, when taahe patient is on […]

Thrombophilia

VTE Risk Assessment Webinar

The International Society on Thrombosis and Haemostasis (ISTH) and the European Thrombosis and Haemostasis Alliance invite you to a joint webinar on Saving Lives by Addressing VTE Risk Assessments: The Role of Public Affairs, to be held virtually on Wednesday, November 4 from 8–9 AM EST. The webinar will discuss the changing role of public […]

Thrombophilia

October 2020 Quick Question: Inflammatory Marker Results

Our October, 2020 Quick Question was, “What inflammation assay does your lab use to assess SARS-CoV-2 progression?” The question attracted 223 votes, a record turnout, but the answers were phrased in a way that directed us to a single answer! Here are the results: CRP: 7% [16] ESR: 0% Ferritin: 1% [2] IL-6: 3% [7] […]

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Quick Question Archive

Oct 28 2020

george

Covid-Coag Controversies 10-18-20 Video

Click here to watch George Fritsma’s 50-minute presentation, COVID-Coag; Controversies and Confusion. This is a follow-up to our September 15 presentation featuring Dr. Andrew Goodwin, and was provided as part of the Imtermountain States Seminar annual meeting in virtual format. Special thanks to Holly Weinberg for her invitation and for coordinating the event.

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Events

Thrombophilia

Webinar Recording: VWF: Friend or Foe

Jan, 2021 QQ: CFX Answers

New: CRYOcheck Hex LA

Jan, 2021 QQ: The Chromogenic Factor X Assay

CLS Journal Hemostasis Articles

DOAC-STOP In Vitro DOAC Removal and LAC

LAC Testing on Warfarin Specimens

VTE Risk Assessment Webinar

October 2020 Quick Question: Inflammatory Marker Results

Covid-Coag Controversies 10-18-20 Video

George Fritsma MS MLS

Cheat Sheets from George

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Quick Question