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June 2023 Quick Question: Factor VIII Inhibitor Bypass

Our June Quick Question asks, “Name the bispecific antibody-based FVIII inhibitor bypass agent,” and lists several recently released therapeutics that are changing the shape of hemostasis disorder treatment. Please select your answer from the column on the right and add your comments below.

Quick Question Archive

May 2023 Quick Question: DTI

Our May 2023 Quick Question asks, “Which DOAC is a direct thrombin inhibitor? Our 70 respondents chose… Dabigatran [Pradaxa]: 56 [80%] Rivaroxaban [Xarelto]: 3 [4%] Apixaban [Eliquis]: 3 [4%] Warfarin [Coumadin]: 7 [10%] Clopidogrel [Plavix]: [2%] Dabigatran is the direct thrombin inhibitor, whereas rivaroxaban and apixaban are direct anti-Xa inhibitors. Clopidogrel is an antiplatelet antithrombotic. […]

Quick Question Archive

Webinar: The Many Faces of VWF, Part 2: Tumor Progression

Fritsma Factor participants, we invite you to view the next installment of our video series “Coag Conversations:” Dr. E. J. Favaloro: The Many Faces of von Willebrand Factor; or Von Willebrand Factor, ADAMTS13, Malignancy, and Beyond Part 2: Von Willebrand Factor and ADAMTS13: Tumor Progression and Beyond, sponsored by BioMedica Diagnostics, Inc.

PERT Consortium

Thanks to Paul Riley, Ph.D., Diagnostica Stago, for his introduction to the Pulmonary Embolism Response Team [PERT] Consortium. For our list of hemostasis-related links, click here. If your association does not appear in the list, please provide the website and link to me [Geo] at [email protected].

Webinar: The Many Faces of VWF Part 1: Von Willebrand Factor and Acquired von Willebrand Syndrome

Fritsma Factor participants, we invite you to view Part 1 of our video: series ‘Coag Conversations’ The Many Faces of von Willebrand Factor; or Von Willebrand Factor, ADAMTS13, Malignancy, and Beyond: Von Willebrand Factor and Acquired von Willebrand syndrome, A Kaleidoscope of Presentations.” This is the first of a three-part series sponsored by BioMedica Diagnostics of […]

Arterial Thrombosis

National Medical Lab Week

Medical Laboratory Professionals Week is an annual celebration of medical laboratory professionals who play a vital role in health care and patient advocacy. In celebration, we’ve posted three new Educational Modules on the topic of hemophilia, titled Hemophilia History, Hemophilia Treatment, and Hemophilia Diagnosis. For Lab Week information, proceed as follows… National Lab Week in […]

April 2023 Quick Question: Prince Alexis

On 3/30/2023 we posted a series of three updated hemophilia audio PowerPoints. Our April 2023 Quick Question asks “What was Russian Prince Alexis’s disorder?” The choices are: Hemophilia A [FVIII deficiency] Hemophilia B [FIX deficiency] Hemophilia C [FXI deficiency] Unknown. You will find the answer under Educational Modules, Hemophilia Part 1: History

Mixed DOACs and the DOAC Clotting Time Test

In a January 2023 letter to the editor, available from the publisher or your library as Exner T, Ellwood L, Dangol M, Favaloro EJ. Mixing factor Xa and thrombin inhibiting direct oral anticoagulants produces a synergistic prolonging effect on most clotting tests. Int J Lab Hematol. 2023 Feb 21. doi: 10.1111/ijlh.14043, investigators examined a DRVVT-based […]

Anticoagulant Therapy

Precision BioLogic Chromogenic FIX Assay Cleared by the FDA

Congratulations to our sponsor, Precision BioLogic Inc., as their CRYOcheck chromogenic factor IX assay was cleared by the US Food and Drug Administration on January 5, 2023. Click here for PBI’s news release. and click “Factor IX Testing and Introduction to CRYOcheck Chromogenic Factor IX” to register for our February 1 webinar featuring special guest […]

Coagulation Factors

The Dilute Thrombin Time Measures DTIs

Here is the abstract of a pre-publication release comparing direct thrombin inhibitor results from the plasma-diluted thrombin time [DTT] to the partial thromboplastin time [PTT]:

Anticoagulant Therapy

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George Fritsma is a medical laboratory scientist, educator, and author. George holds faculty appointments with Rutgers University and Michigan State University, and is a member of the International Society on Thrombosis and Hemostasis, American Association of Clinical Chemists, and American Society for Clinical Laboratory Science.

Cheat Sheets from George

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