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Anticoagulant Therapy

May 24 2012
george

HIT Kits

From Ginger Weeden, MLS (ASCP)cm, Bio-Rad Laboratories: George, What heparin-induced thrombocytopenia with thrombosis (HIT) testing is available in the US? I’m wondering how many manufacturers there are. Thanks for any information. Hi, Ginger, and thanks for your question. All the C14 serotonin release assay methods (washed platelets) available from reference labs are laboratory-developed tests. Here are the manufacturers I […]
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Anticoagulant Therapy
May 16 2012
george

Who Uses the Hybrid Curve?

Most of us have maintained separate calibration (reference) curves for our chromogenic anti-Xa heparin assays, one each for standard unfractionated heparin (UFH) and low molecular weight heparin (LMWH, enoxaparin, Lovenox), and more recently, the synthetic pentasaccharide, fondaparinux (fonda, Arixtra). Frequent contributor (friend and colleague) Dave McGlasson (Wilford Hall USAF Medical Center) has published two articles on the […]
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Anticoagulant Therapy
May 11 2012
george

Ecarin Clotting Time: Dr. Zuckerman

On April 29, Crystal Azavedo asked about laboratories that monitor dabigatran with the ecarin clotting time (ECT). Last week at the Thrombosis and Hemostasis Summit of North America I became reacquainted with long-time colleague, Dr. Leon Zuckerman, founder of Coagulation Consultants of Des Plaines, Illinois. Coagulation Consultants is a full-service hemostasis reference laboratory that also offers the ECT. It was good to see Dr. […]
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Anticoagulant Therapy
May 7 2012
george

Reprise: Validating POC INRs

Back to our April 24 anticoagulation clinic manager’s question about when to validate a prolonged point of care (POC) prothrombin time with international normalized ratio (PT/INR). George spoke with representatives of Roche Diagnostics, distributor of Coag-U-Chek instruments, while attending the May 3–5 Thrombosis and Hemostasis Summit of North America meeting in Chicago. While Roche contends this is a local decision and […]
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Anticoagulant Therapy
May 6 2012
george

Reprise: Validating POC INRs

Back to our April 24 anticoagulation clinic manager’s question about when to validate a prolonged point of care (POC) prothrombin time with international normalized ratio (PT/INR). George spoke with representatives of Roche Diagnostics, distributor ofCoag-U-Chek instruments, while attending the May 3–5 Thrombosis and Hemostasis Summit of North America meeting in Chicago. While Roche contends this is a local decision and […]
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Anticoagulant Therapy
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George Fritsma MS MLS

George Fritsma is a medical laboratory scientist, educator, and author. George  is a member of the International Society on Thrombosis and Hemostasis, the International Society for Laboratory Hematology, and the American Society for Clinical Laboratory Science.

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What VWD subtype Is caused by a VWF gain of function?