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More on Altuviiio Assays

This post with its dialogue between Dr. Uljon and Dr. Sadeghi-Khomami describes how to minimize EHL measurement discrepancies. Read to the end! Here’s a post from Sacha N. Uljon MD PhD, Massachusetts General Hospital (MGH) and Brigham and Women’s Hospital (BWH), Boston, US, describing their experience with Altuviiio measurement using a one-stage clot-based assay and […]

Bleeding Disorders

December 2024 Cheat Sheet

Click here to receive your December 2024 Cheat Sheet. If you would like to join the list of participants who receive their monthly Cheat Sheet via email, please complete the brief form on the home page. The Cheat Sheet and your partnership with Fritsma Factor are free.

November 2024 QQ: Cryoprecipitate

Our November 2024 Quick Question, which attracted 28 responses, asked, “Who invented cryoprecipitate?” Dr. E. J. Kohn: 1 (4%) Dr. Judith Pool: 19 (68%) Dr. Armand Quick: 3 (11%) Dr. Rudolph Virchow: 4 (13%) Dr. Kenneth Brinhous: 1 (4%) Comments: Cryoprecipitate (Cryo) was developed and produced by Judith Pool, PhD, 1919–1975, from Stanford University in […]

Quick Question Archive

Clot Detection in Whole Blood Specimens

I (Geo) received this message on 11-27-24 from Dr. Ludwig Albornoz: After a simple search on Google, we landed on your website, regarding a practice of detecting and removing fibrin and or blood clots in clinical laboratory blood specimens by using a mechanical method, either plastic or wooden rods, which I introduced for use in […]

Specimen Management

Clot Club: Hemophilia Therapy

on 11/13/2024, Fritsma Factor colleague Dave McGlasson, Clot Club contributor, posted Extended Half-life (EHL) Testing for Factor VIII (FVIII) and Factor IX (FIX) Therapies. His entry provides comprehensive laboratory assay information for managing all current factor concentrates and bypassing therapies.

Bleeding Disorders

Coag Conversation: ITP and Platelet Functional Disorders, Part 2

Here is the second of our three-part series, “A Coag Conversation: ITP and Inherited Platelet Function Disorders.” featuring Michele Lambert, MD, MSTR, interviewed by George Fritsma and sponsored by BioMedica Diagnostics, Inc. Dr. Lambert is Associate Professor of Pediatrics at the Pearlman School of Medicine, University of Pennsylvania and Pediatric Hematologist at the Children’s Hospital […]

Platelet Function Testing

Agent Orange and Lupus Anticoagulant?

I (Geo) received an 11-7-24 message from Steve Montag, whose oncologist states that his lupus anticoagulant is “more than likely” caused by Agent Orange exposure. We could only find a single reference associating antiphospholipid antibodies to the Gulf War Syndrome, but nothing linking Agent Orange. Please comment below if you have seen this or can […]

Low VWF Classification Dropped by the ISTH

The September 2024 edition of the Journal of Thrombosis and Haemostasis contains a helpful editorial describing the most recently developed classification of von Willebrand disease that drops the classification “Low von Willebrand Factor” that we’ve used to describe people whose VWF level is between 30–50 VWF Units/dL. Click here for the article: Low VWF Enigma […]

Bleeding Disorders

Hot Topics in Hemostasis: Nomenclature Standardization

Frequent contributor David L. McGlasson is featured in the Differential Discussions series hosted by Assistant Professor David Cabral, MBA, MLS(ASCP)cm, SH(ASCP)cm of the University of Massachusetts Dartmouth, and Assistant Professor Malissa Norfolk, MBA, MLS(ASCP)cm, SH(ASCP)cm, of the University of Maine-Augusta faculty. Click here to meet Malissa and David, and to hear Mr. McGlasson’s discussion of […]

Coagulation Factors

November 2024 Cheat Sheet

Dear Fritsma Factor participants, here is your November 2024 Cheat Sheet. You will soon receive your private copy by email. If you want to be on the Cheat Sheet list, please complete the form on the right of your screen.

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George Fritsma is a medical laboratory scientist, educator, and author. George holds faculty appointments with Rutgers University and Michigan State University, and is a member of the International Society on Thrombosis and Hemostasis, American Association of Clinical Chemists, and American Society for Clinical Laboratory Science.

Cheat Sheets from George

Quick Question