From Heather DeVries, Indiana University Health. Hi George! We use the DDHS kit from IL on our TOP series instruments. There is a cancer patient at one of our facilities who has not been able to get a dimer result while on Xarelto. From the error codes, it looks like it would be human anti-mouse antibody (HAMA) interference. But after the patient was taken off Xarelto, they are able to get a result. It is high, but valid. I read the posts from last year about possible false elevation while on Xarelto, this case seems to be a bit different. Would the HAMA go away? The first four draws did not give results. But now, after being off Xarelto for 2 weeks, the lab is getting a result. Thanks!
Hi, Heather, thanks for another great question. I’m wondering if the kit is picking up interference from the Xarelto itself. I’ll be soliciting additional comments from my IL colleagues.