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Unable to Obtain Dimer Result on Xarelto

From Heather DeVries, Indiana University Health. Hi George!  We use the DDHS kit from IL on our TOP series instruments. There is a cancer patient at one of our facilities who has not been able to get a dimer result while on Xarelto. From the error codes, it looks like it would be human anti-mouse antibody (HAMA) interference. But after the patient was taken off Xarelto, they are able to get a result. It is high, but valid. I read the posts from last year about possible false elevation while on Xarelto, this case seems to be a bit different. Would the HAMA go away? The first four draws did not give results. But now, after being off Xarelto for 2 weeks, the lab is getting a result. Thanks!

Hi, Heather, thanks for another great question. I’m wondering if the kit is picking up interference from the Xarelto itself. I’ll be soliciting additional comments from my IL colleagues.

Comments (1)
Anticoagulant Therapy
Mar 3, 2017 5:47pm

Update on this patient – we
Update on this patient–we sent out for the dimer to be done by manual ELISA method. It was negative!

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