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Quick Question: PT substitute

Our November, 2019 Quick Question asks, “What may you substitute for the PT when LAC prolongs the PT?” This question addresses the unreliability of the PT for monitoring Coumadin therapy when lupus anticoagulant interferes by prolonging the result. It is also relevant to PT prolongation by fibrinogen deficiency or factors II, V, VII, or X deficiency. Please answer the survey and provide your comments below or by emailing George at [email protected].

Comments (1)
Anticoagulant Therapy
RobynColeman
Nov 4, 2019 9:56pm

Chromogenic X is not always
Chromogenic X is not always available as a routine test, so an awareness of how lupus AC affects your reagents is vital. Robyn

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