Dear George, I work in a large midwest reference laboratory. We are looking at bringing in the Prot S free latex test. Have you seen any comparison studies between manufacturers’ kits that I could go out on the internet and read? Thanks, Pamela L. Pool, Section Specialist for Coagulation.
Hello, Pamela, thank you for your question. Yes, please access Mulder R, Ten Kate MK, Kluin-Nelemans HC, Mulder AB. Low cut-off values increase diagnostic performance of protein S assays. Thromb Haemost 2010;104:618–25. This group has examined the predictive values of several protein S activity and antigen assays. Also, I invite our participants to provide their favorite references or local comparison studies. Geo.