June 2026 QQ: VWF Gain of Function

In keeping with our “100 Years of VWD” theme, our June 2026 Quick Question, which appears in the right-hand column, asks, “What VWD subtype is caused by a VWF gain of function?” Gain of function refers to VWF with enhanced binding avidity to the platelet GP1b binding site. For assistance, navigate to our Informative Module, von Willebrand Disease, or turn to Sarkar MK, Fritsma GA. Hemorrhagic Disorders and Laboratory Assessment in Keohane EM, Butina MM, Mirza KM, Walenga JM. Rodak’s Hematology: Clinical Principles and Applications, Seventh Edition, Elsevier, 2025. We invite comments about this Quick Question and VWD in general using the “comments” section below or emailing [email protected].