From Heather DeVries at Indiana University Health. Hello George! In a system meeting recently, our procedure for evaluating new lot calibrator material was discussed. Currently, we require sites to run 5 points of QC after calibrating with a new lot. If the mean of those 5 points is within 20% of the established mean, we are done. If there is a shift where the mean is >20% different, we require sites to run 20 total points over 3 days to re-establish mean. Smaller sites consider this a waste of reagent, even though I don’t believe we have ever had to run 20 points. Even 5 points seems too much for them. How do other facilities handle new lot calibrator material? Thanks!
Hi, Heather, and thank you for your question. Am I correct to conclude the 5 points of QC, or the 20 points, when necessary, refers to control material, which, along with reagents to run the assays seems like a modest use of materials, but I’d like to learn what our participants are doing. Geo.