HIT Kits

From Ginger Weeden, MLS (ASCP)cm, Bio-Rad Laboratories: George, What heparin-induced thrombocytopenia with thrombosis (HIT) testing is available in the US? I’m wondering how many manufacturers there are. Thanks for any information.
Hi, Ginger, and thanks for your question. All the C14 serotonin release assay methods (washed platelets) available from reference labs are laboratory-developed tests. Here are the manufacturers I know who provide immunoassays designed to detect anti-platelet factor-4 (PF4)-heparin antibodies that are associated with HIT :

• Akers Biosciences PIFA Heparin/PF4 Rapid Assay (Two-minute lateral immunoassay)
• Gen-Probe LIFECODES PF4 (what I’ve always called GTI Laboratories)
• HYPHEN BioMed Anti-(h)-PF4, available through Aniara
• Instrumentation Laboratory HIT-Ab (PF4-H) (RUO for North America)
• Sekisui Diagnostics (formerly American Diagnostica) IMMUCLONE Platelet Factor 4 ELISA (RUO)
• Stago Asserachrom HPIA (ELISA)

If I’ve missed any suppliers, I hope our participants will fill us in. Geo