Our February, 2020 Quick Question, which drew 114 answers, asks, “For chronic bleeds, poor wound healing with normal PT, PTT, FG and platelets, what assay should be next?”
- Factor VIII: 18% (21)
- Factor IX: 3% (3)
- Factor XI: 4% (5)
- Factor XIII: 75% (85)
The question was meant to draw us to factor XIII deficiency as it references poor wound healing. In defense of those who chose factor VIII deficiency as a possibility, a moderately low factor VIII level may not necessarily prolong the PTT in cases where the PTT is conservatively calibrated to prolong at levels below 30 U/dL. However, given the normal platelet parameters, factor XIII deficiency is the most likely situation.