From Jasmina Ahluwalia: Hi George, Is there any advantage of choosing an immunotubidimetric (latex immunoagglutination, LIA) assay over the enzyme-linked immunosorbent assay (ELISA) for von Willebrand factor antigen (VWF:Ag)?
Hello, Jasmina, and thank you for waiting for this answer while we updated the Fritsma Factor site. The two methods have similar sensitivity, specificity, linearity, and coefficient of variation (CV%) characteristics, however the LIA is usually designed for automated applications, where the analytical time is often less than 10 minutes. The ELISA is usually performed manually, or on an automated fluid manager, and requires approximately 2.5 hours to complete. Your choice depends on how your laboratory is equipped. Geo.
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