From Julia Nailling: What delta checks do laboratories commonly use for autoverification of prothrombin time with international normalized ratio (PT/INR), partial thromboplastin time (PTT), fibrinogen, and D-dimer?
Hi, Julia, thank you for your question. I’ll let our participants respond to this, as our own laboratory doesn’t use autoverification or delta checks, although we do carefully inspect results before they are released. The anecdotal answer I’ve heard is a 10% change, similar to my speculative answer to the previous question about reference ranges, but the limits may be adjusted for each parameter based on clinical significance. I also received this response from Chris Ferrell, University of Washington, “Sorry George, We don’t have a specific rule. It’s totally up to the director to decide.”
Julia, this is an opportunity for a new Quick Question, stay tuned!