type I cryoglobulinemia [monoclonal IgM kappa]. Rae’s team team ordered a PFA but they were unable to obtain results due to hyperviscosity.  PT/PTT = 13.9/24.7. They are planning to test FVIII via the 0ne-stage clotting assay, VWF Ag by Liatest, and a ristocetin cofactor by platelet agglutination.  Rae is concerned that at least the VWF Ag and the VWF:RCo could be inaccurate due to the protein changes. Rae also asked if we could perform clot-based testing on pheresis plasma.