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Thrombophilia

Mar 14 2026
george

Review: Antiphospholipid Antibodies and Cardiovascular Thrombosis

Go to your medical library for this pre-print review: Rashedi S, Leyva H, Siddiqui SA, et al. Antiphospholipid antibodies and cardiovascular thrombosis. Nat Rev Cardiol. 2026. doi: 10.1038/s41569-026-01269-9. PMID: 41807758. Abstract Antiphospholipid antibodies (aPL) are directed against phospholipids and phospholipid-binding proteins. Laboratory assays used to detect aPL include serological tests for aPL against β2-glycoprotein 1, […]
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Thrombophilia
Mar 4 2026
george

Research Report Examines Efficacy of Chemiluminescence HIT Assay

Here is an open-access article describing the efficacy of a chemiluminescence HIT assay: Bowyer A, Kohama K, Patel I, et al’A new, rapid, chemiluminescence enzyme assay for the detection of heparin-induced thrombocytopenia: a comparison between functional and immune heparin-induced thrombocytopenia assays, Res Prac in Thrombosis and Haemostasis,2026;10, 103373, ISSN 2475-0379, https://doi.org/10.1016/j.rpth.2026.103373. Abstract Background Heparin-induced thrombocytopenia […]
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Thrombophilia
Feb 21 2026
george

Review: Non-antithrombotic Strategies for Venous Thromboembolism Prophylaxis

Check with your medical library for this provocative review of VTE prevention: Gurumurthy G, Thachil J. Nonanticoagulant strategies for venous thromboembolism prophylaxis. Semin Thromb Hemost. 2026;52:236–47. doi: 10.1055/a-2712-3534. PMID: 41092960. Abstract Venous thromboembolism (VTE) remains a major cause of preventable morbidity and mortality. Prophylaxis with anticoagulation is limited by bleeding risk, contraindications, and patient-specific factors. […]
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Thrombophilia
Feb 13 2026
george

Letter to 2024 NEJM Links Adenoviral Anti-PF4 to VITT

Click here for the full news release from Flinders University News: New research, led by Flinders University and international experts, has finally uncovered how a rare blood-clotting condition can occur after some COVID-19 adenovirus-based vaccines or after a natural adenovirus infection. First paragraph: To the Editor: Disorders caused by antibodies against platelet factor 4 (PF4) gained […]
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Arterial Thrombosis
Feb 9 2026
george

Normalized Activated Protein C Sensitivity Ratio Predicts VTE in OCR

Here is an open-access report on a noteworthy primary research piece detailing an assay that predicts VTE risk associated with oral contraceptives: Morimont L, Creinin MD, Gaspard U, Foidart JM, and Douxfils J. Predicting venous thromboembolism risk from an endogenous thrombin potential-based normalized activated protein C sensitivity ratio assay: toward early assessment of combined oral […]
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Thrombophilia
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George Fritsma MS MLS

George Fritsma is a medical laboratory scientist, educator, and author. George  is a member of the International Society on Thrombosis and Hemostasis, the International Society for Laboratory Hematology, and the American Society for Clinical Laboratory Science.

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Which is NOT an endogenous coag control protein?