Nov 28 2025

george

December 2025 Quick Question: Control Proteins

Our December 2025 Quick Question is another quiz, this time about the coagulation control systems. It asks, “What plasma control protein acts against factor IIa (FIIa, thrombin) and factor Xa (FXa, activated FX)? Please answer and add your comment below.

read more

Comments (0)

Quick Question Archive

Nov 28 2025

george

November 2025 QQ Results: Stuart-Prower Factor

Our November 2025 Quick Question asked, “Which is the numeral for the Stuart-Prower factor? Here are the results from our 31 participants: V: 0 (0%0 VII: 3 (10%) X: 19 (61%, correct) XI: 5 (16%) XII: 4 (13%) We scored well. Beginning with the International Committee on Nomenclature’s 1958 recommendations, we began using Roman numerals […]

read more

Comments (1)

Quick Question Archive

Oct 28 2025

george

November 2025 QQ: Stuart-Prower Factor

Our November 2025 Quick Question tests our historical knowledge. Not long ago, we learned about various names for the coagulation factors; e. g., proaccelerin, proconvertin, and plasma thromboplastin antecedent. Some factor names were proper nouns, for example, Hageman factor, Fletcher factor, and Fitzgerald factor. This month’s question asks you to identify the Stuart-Prower factor by […]

read more

Comments (0)

Quick Question Archive

Oct 28 2025

george

October 2025 QQ: Reporting Assay Uncertainty Data Summary

Our October 2025 Quick Question was a poll that asked, “Do you support publishing assay uncertainty data with all results?” The poll attracted 13 respondents who answered: Yes: 4 (31%) No: 8 (62%) It depends: 1 (7%) While the response was small, our question attracted several vigorous comments (click). Generalizing, this hourglass figure, cited in Stroobants […]

read more

Comments (0)

Quick Question Archive

Sep 29 2025

george

October 2025 QQ: Reporting Assay Uncertainty Data

Please refer to our August 29, 2025 discussion, “Hemostasis Assay Statistical Variation.” In this post, we linked the article, Mullier F, Gouin-Thibault I, Meijer P, et al. Time to integrate measurement uncertainty in method comparison and interpretation of hemostasis laboratory assays. Res Practice Thromb Hemost 2025: 9, https://doi.org/10.1016/j.rpth.2025.102993. The authors contend that we should report uncertainty […]

read more

Comments (7)

Quick Question Archive

Sep 29 2025

george

September 2025 QQ: Viscoelastometry Discussion

Our September 2025 Quick Question asked, “What viscoelastometry device is employed at your facility?” A modest group of thirteen participants answered… TEG 6s: 4 (31%) TEG 5000: 2 (15%) ROTEM: 5 (39%) Sonoclot: 0 Hemosonics Quantra: 2 (15%) The TEG 5000 was developed in 1948, and the Sonoclot in 1975; both represent the pioneering phase […]

read more

Comments (0)

Quick Question Archive

Sep 1 2025

george

September 2025 QQ: Viscoelastometry

Our September 2025 QQ is a poll that asks, “What viscoelastometry device is employed at your facility?” Often, VET devices are employed in the OR or ER, both near-patient applications. For many years, we’ve used the time-honored Thromboelastograph (TEG) 5000 or its competitor, the Sonoclot, both of which are available worldwide. Newer offerings include the […]

read more

Comments (0)

Quick Question Archive

Sep 1 2025

george

August 2025 QQ: Direct Oral Anticoagulants

Our August 2025 QQ is a poll that asked, “What AC does your provider prescribe for non-valvular AFIB?” Here are the choices made by our 18 responders: Apixaban (Eliquis) 10 (56%) Clopidogrel (Plavix) 0 Dabigatran (Pradaxa) 3 (16%) Rivaroxaban (Xarelto) 1 (6%) Warfarin (Coumadin) 4 (22%) This QQ arose from discussions with my (Geo) PCP […]

read more

Comments (0)

Anticoagulant Therapy

Jul 30 2025

george

August 2025 QQ: Anticoagulant Choice for AFIB

Our August 2025 Quick Question asks, “What AC does your provider prescribe for non-valvular AFIB?” I (Geo) asked my PCP this question at my annual wellness visit on July 29, 2025. Not a personal concern, just curious. Please provide your answer on the right and add your comments, which will appear in our end-of-month summary.

read more

Comments (0)

Quick Question Archive

Jul 29 2025

george

July 2025 QQ: Hemophilia Rebalancing Therapy

Our July 2025 Quick Question asked, “Which is a hemophilia ‘rebalancing’ therapeutic?” The question attracted a modest 22 participants, perhaps an indication that rebalancing therapy was only FDA-approved in 2025 and awaits approval in Canada and Europe. Here are your responses… Valoctocogene roxaparvovec-rvox (ROCTAVIAN) 3 (14%) Efanesoctocog alfa (ALTUVIIIO) 1 (4%) Emicizumab (HemLibra) 7 (32%) […]

read more

Comments (0)

Quick Question Archive