Monitoring Direct Thrombin Inhibitors and Oral Anti-Xa Antithrombotics

Presenter: Dorothy Adcock-Funk, MD Panelists: Kandice Kottke-Marchant, MD, PhD; Marisa B. Marques, MD; John D. Olson, MD, PhD Moderator: George A. Fritsma, MS MT (ASCP) Precision BioLogic Laboratory Medicine Roundtable, June 20 and 21, 2008, Dartmouth, Nova Scotia In addition to Wendy Porteous, Steve Duff and Michael Scott, I would like to acknowledge Dean Willett, […]

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Jul 3 2008

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D-Dimer Reports: Some Alarming Discoveries

Presenter: John D. Olson, MD, PhD Panelists: Dorothy Adcock Funk, MD, Kandice Kottke-Marchant, MD, PhD, Marisa B. Marques, MD Moderator: George A. Fritsma Precision BioLogic Laboratory Medicine Roundtable, June 20 and 21, 2008, Dartmouth, Nova Scotia First, I’d like to thank Wendy Porteous, Steve Duff, Michael Scott, and all the Precision BioLogic Inc. participants who […]

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Reagent sensitivity and clinical interpretation

Here’s an interesting question from Anita D’Antonio. Several of our hospitals Hematologists/Oncologists have concerns with the sensitivity of the reagent we use for Prothrombin testing. The reagent is Diagnostica Stago STA-Neoplastine Cl Plus with a 1.32 ISI. They believe the reagent is too sensitive and is generating needless consults and follow-up testing on patients who […]

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Reagent sensitivity and clinical interpretation

Here’s an interesting question from Anita D’Antonio. Several of our hospitals Hematologists/Oncologists have concerns with the sensitivity of the reagent we use for Prothrombin testing. The reagent is Diagnostica Stago STA-Neoplastine Cl Plus with a 1.32 ISI. They believe the reagent is too sensitive and is generating needless consults and follow-up testing on patients who […]

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Guest blog posts

I will be on vacation until July 16, so I will not be making any blog posts. However I have requested David McGlasson MS, CLS/NCA, from LackLand AFB to respond to any technical questions that may be posed while I am away. Also, I am very happy to tell you that during the next two […]

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Quick Question: HIT Screens

Our quick question of June 23-27 asked how each of us is screening for heparin-induced thrombocytopenia (HIT). All seven respondents chose the GTI ELISA PF4/IgG/A/M kit. None chose heparin induced platelet aggregometry, serotonin release assay, or another GTI ELISA kit besides GTI. The issue of HIT testing was featured in Precision BioLogic’s June 19-20 roundtable, […]

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How to Report HIT ELISA Results

Here is an interesting question from Dr. Michael D. Blechner of the University of Kentucky: First I would like to compliment you on a great web site; an extremely valuable resource for myself as well as our residents. Second, I would love for you to do a followup “Quick Question” to evaluate how folks are […]

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Precision BioLogic Round Table Discussion

Precision BioLogic Inc., the folks who sponsor the Fritsma Factor, hosted a June 19-20 roundtable at their beautiful new facility in Dartmouth, Nova Scotia, across the harbor from Halifax. Participants were Dorothy (Dot) Adcock-Funk, MD, Medical and Laboratory Director of Esoterix Coagulation in Englewood, CO; Kandice Kottke-Marchant, MD, PhD, Chair of the Department of Pathology […]

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New Chest Journal Antithrombotic Guidelines

Dr. Marisa B. Marques, director of the University of Alabama at Birmingham Hospital Special Coagulation Laboratory reports the American College of Chest Physicians Eighth ACCP Conference on Antithrombotic and Thrombolytic Therapy has released “Antithrombotic and Thrombolytic Therapy: 8th Edition Guidelines.” The guidelines are available free online to non-subscribers at Chest 2008:133 (6 suppl) . This […]

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Factor Levels in Hemophilia

Mary Paoli of Palmetto Health asks, “When hemophilia is classified as severe, moderate or mild, are factor VIII activity levels (FVIII:C), reported in percentage, or factor VIII antigen (FVII:Ag), reported in U/dL? Thank you for your question, Mary. When a newborn boy is at risk of hemophilia, his plasma is tested using the plasma-based factor […]

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Monitoring Direct Thrombin Inhibitors and Oral Anti-Xa Antithrombotics

D-Dimer Reports: Some Alarming Discoveries

Reagent sensitivity and clinical interpretation

Reagent sensitivity and clinical interpretation

Guest blog posts

Quick Question: HIT Screens

How to Report HIT ELISA Results

Precision BioLogic Round Table Discussion

New Chest Journal Antithrombotic Guidelines

Factor Levels in Hemophilia

George Fritsma MS MLS

Cheat Sheets from George

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