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Anticoagulant Therapy

Oct 30 2025
george

Case Study: Measuring TAT Complex in LVAD Implantation

Check with your library for this article describing the TAT Assay in LVAD Implantation. Ling L, Liu C, Zhou J. Thrombin-antithrombin complex might be a promising parameter for monitoring anticoagulation in the early postoperative period after LVAD implantation. Lab Med. 2025 ;56:423–7. doi: 10.1093/labmed/lmae113. PMID: 40085520. Abstract Introduction: Appropriate bridging anticoagulation is critical in the […]
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Anticoagulant Therapy
Oct 27 2025
george

A Coag Conversation: Alternate Warfarin Monitoring When the Prothrombin Time is Unreliable – Part 1

Join me (Geo) and guest speaker Dr. Nicole Zantek, MD, PhD, Medical Director of the Special Coagulation Laboratory, Professor, Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, who discusses the pathophysiology of antiphospholipid antibodies, and alternative methods to monitor warfarin and DOAC anticoagulation in patients diagnosed with antiphospholipid syndrome. This is the […]
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Anticoagulant Therapy
Oct 25 2025
george

International Symposium on Intensive Care and Emergency Medicine: Nebulizer Delivery of Unfractionated Heparin

Thanks to Dave McGlasson, MS, MLS, for the heads-up about this open-access review of the International Symposium on Intensive Care and Emergency Medicine (Click Here). Bateman RM, Sharpe MD, Jagger JE, et al. 36th International Symposium on Intensive Care and Emergency Medicine: Brussels, Belgium. 15–18 March 2016. Crit Care. 20160;20(Suppl 2):94. doi: 10.1186/s13054-016-1208-6. Erratum in: […]
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Anticoagulant Therapy
Oct 21 2025
george

Algorithm for DOAC Dipstick Application

Click here for the open-access article: Harenberg J, Gosselin RC, Cuker A, et al. Algorithm for rapid exclusion of clinically relevant plasma levels of direct oral anticoagulants in patients using the DOAC dipstick: an expert consensus paper. Thromb Haemost. 2024;124:770–7. doi: 10.1055/a-2261-1811. PMID: 38316416. Abstract Background With the widespread use of direct oral anticoagulants (DOACs), there […]
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Anticoagulant Therapy
Sep 17 2025
george

A Review of Current and Developing DOAC Reversal Agents

Check with your medical library for this comprehensive review of current and developing DOAC reversal agents:  Gómez-Outes A, Suárez-Gea ML, Lecumberri R. When and how to use reversal agents for direct oral anticoagulants? Curr Cardiol Rep. 2023;25:371–80. doi: 10.1007/s11886-023-01858-x. PMID: 36976497. Abstract Purpose of review: Our objective is to describe currently available reversal agents for […]
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Anticoagulant Therapy
Sep 12 2025
george

Heparin Resistance in Pancreatitis

Click this open-access article to read about heparin resistance in an acute pancreatitis patient with a normal antithrombin level: Rongqin D, Zhexin B, Yuzhi L, et al. Heparin resistance in a patient with severe acute pancreatitis: a case report. Lab Med. 2025;56:570–6. doi: 10.1093/labmed/lmae126. PMID: 40237706; PMCID: PMC12417076. Here’s the abstract: Introduction: Severe acute pancreatitis […]
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Anticoagulant Therapy
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George Fritsma MS MLS

George Fritsma is a medical laboratory scientist, educator, and author. George  is a member of the International Society on Thrombosis and Hemostasis, the International Society for Laboratory Hematology, and the American Society for Clinical Laboratory Science.

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Quick Question

Which is NOT an endogenous coag control protein?