Mar 12 2019

george

FVIII and FIX Activity Survey

We hope that you’ve taken the opportunity to respond to our specimen integrity survey, which remains open for a few more days. We now offer a second survey developed by Precision BioLogic Inc., asking about new approaches to monitoring our many new formulations of factor VIII and factor IX concentrate. This has become a consuming issue […]

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Anticoagulant Therapy

Mar 6 2019

george

Hyperglycemia and Stroke Outcome

The iSPOT study links treatment outcomes for acute isechemic stroke in hyperglycemic patients with markers of tissue factor pathway activation, as reported on March 5, 2019 in The Heart.org. Click or tap here for details.

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Arterial Thrombosis

Mar 6 2019

george

Andexxa Conditional Approval in Europe

The Heart.Org reports that the the Rivaroxaban and Apixaban reversal agent Andexxa (andexanet alpha) has earned conditional approval by the European Medicines Agency. Click or tap here for details.

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Anticoagulant Therapy

Mar 1 2019

george

Specimen Integrity Survey Quick Question

Our March, 2019 Quick Question consists of a Survey Monkey survey (click or tap) on specimen integrity. Please see the entry for a full explanation.

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Quick Question Archive

Mar 1 2019

george

Quick Question: 41 YO Man With GI Bleeding Response

Our February, 2019 Quick Question was a case study entitled, “41-YO Man with GI Bleeding” (click or tap to review). For 56 responders, the answers and tallies were… Vitamin K deficiency 9% (5) Moderate liver disease 57% (32) Functional platelet disorder 4% (2) Disseminated intravascular coagulation 21% (12) Other: please provide a written response 9% […]

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Bleeding Disorders

Feb 27 2019

george

February Quick Question Reminder

Just a reminder, only two more days to answer our February 1 Quick Question. For our March Quick Question we will be turning to our Specimen Integrity Survey. Watch for your monthly Cheat Sheet early next week.

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Quick Question Archive

Feb 24 2019

george

Eptifibatide Effect on Platelet Aggregometry

Do any Fritsma Factor participants have experience with the platelet aggregation effects of eptifibatide (integrelin), or of any of the GP IIb/IIIa inhibitors. Do you have experience with the Werfen Accumetrics VerifyNow IIb/IIIa assay? If so, please comment below or email [email protected].

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Antiplatelet Therapy

Feb 21 2019

george

Specimen Integrity Survey

With thanks to Stephen Duff, George was recently introduced to Franziska Broell of Halifax. Dr. Broeli has developed a device, the VitalTag, that is able to measure various specimen stresses such as storage time, temperature, and physical stresses. Click or tap here for preliminary information on the VitalTag. Dr. Broell has developed a questionnaire to […]

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Specimen Management

Feb 20 2019

george

Andexxa Study Results

On February 15, Heart.org reviewed the outcomes of a study published in the New England Journal documenting the clinical efficacy of andexanet alfa (Andexxa). The study is the first to illustrate clinical outcomes, cessation of bleeding, compared to previous data that used laboratory outcomes as evidence for reversal. Click or tap here to see the […]

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Anticoagulant Therapy

Feb 18 2019

george

Coumadin and Cortisone Interaction

A subscriber asks, I just received this week a cortisone shot in my knee. I am and have been on Warfarin for many years. Since the shot I seem to be dizzy and light  headed. Is this common? Hello, and thank you for your question, as a laboratory scientist I can comment that there is […]

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Anticoagulant Therapy