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World Hemophilia Day April 17, 2023

Click here for the World Federation of Hemophilia on April 17, 2023, World Hemophilia Day. The theme this year is “Access for All: Prevention of bleeds as the global standard of care.” The call to action is to come together and advocate with local policymakers and governments for improved access to treatment and care with […]

Bleeding Disorders

March 2023 CAP Today: Over-transfusion

The March 2023 Issue of CAP Today offers an anecdotal study on over-transfusion. The data could be enhanced with a review of laboratory assays such as viscoelastometry that help direct the need for red cells, platelets, or component-based hemostasis control. If you have experience with coag-based transfusion monitoring, please comment.

Bleeding Disorders

Webinar: The Many Faces of VWF Part 1: Von Willebrand Factor and Acquired von Willebrand Syndrome

Fritsma Factor participants, we invite you to view Part 1 of our video: series ‘Coag Conversations’ The Many Faces of von Willebrand Factor; or Von Willebrand Factor, ADAMTS13, Malignancy, and Beyond: Von Willebrand Factor and Acquired von Willebrand syndrome, A Kaleidoscope of Presentations.” This is the first of a three-part series sponsored by BioMedica Diagnostics of […]

Arterial Thrombosis

Discrepant PT and INR Results

From Soha Abuelela. I’m using the ACL Pro Elite for PT and PTT testing in my lab using Hemosil Recombiplastin 2G reagent but I frequently notice sample results showing normal PT time in seconds with normal concentration but the INR is above the reference interval! Could you please help me with possible causes and your […]

Anticoagulant Therapy

April 2023 Cheat Sheet

Here is your April 2023 Cheat Sheet. Watch for your copy via email soon and happy Spring!

VWF: Friend or Foe

I [Geo] will present, “Von Willebrand Factor, Friend or Foe: MA, TTP, aHUS, STEC-HUS, MAHA, PLEX, TIC, ADAMTS13, VWF What Does it All Mean?” for the combined ASCLS-Alaska, -Washington, and -Oregon on Friday, April 21, 1–2 CDT, and again for ASCLS-North Dakota on Friday, April 28, 2–3 CDT. These presentations are virtual. Click here for […]

National Medical Lab Week

Medical Laboratory Professionals Week is an annual celebration of medical laboratory professionals who play a vital role in health care and patient advocacy. In celebration, we’ve posted three new Educational Modules on the topic of hemophilia, titled Hemophilia History, Hemophilia Treatment, and Hemophilia Diagnosis. For Lab Week information, proceed as follows… National Lab Week in […]

April 2023 Quick Question: Prince Alexis

On 3/30/2023 we posted a series of three updated hemophilia audio PowerPoints. Our April 2023 Quick Question asks “What was Russian Prince Alexis’s disorder?” The choices are: Hemophilia A [FVIII deficiency] Hemophilia B [FIX deficiency] Hemophilia C [FXI deficiency] Unknown. You will find the answer under Educational Modules, Hemophilia Part 1: History

March 2023 Quick Question: Apixaban Reversal

Our March 2023 Quick Question asked, “Which reversal agent is effective in managing apixaban overdose?” Our 45 respondents chose: rFVIIa [NovoSeven]: 4 [9%] Andexanet alfa: 28 [62%] Idarucizumab: 5 [11%] Vitamin K: 6 [13%] FFP: 2 [5%] Before direct reversal agents became available, DOAC overdose-related bleeding was treated by attempting to absorb undigested anticoagulant from […]

Anticoagulant Therapy

Dabigatran Recall

Thanks to Dave McGlasson for forwarding this Medscape bulletin [click] announcing Ascend Laboratories’ recall of 10 dabigatran lots due to the detection of the nitrosamine impurity, N-nitroso-dabigatran, a potential carcinogen.

Anticoagulant Therapy

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George Fritsma is a medical laboratory scientist, educator, and author. George is a member of the International Society on Thrombosis and Hemostasis, the International Society for Laboratory Hematology, and the American Society for Clinical Laboratory Science.

Cheat Sheets from George

Quick Question