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PERT Consortium

Thanks to Paul Riley, Ph.D., Diagnostica Stago, for his introduction to the Pulmonary Embolism Response Team [PERT] Consortium. For our list of hemostasis-related links, click here. If your association does not appear in the list, please provide the website and link to me [Geo] at [email protected].

Antiphospholipid Antibodies in Gulf War Syndrome

Thanks to hemostasis researcher Dave McGlasson for sending this article that indicates lupus anticoagulant as an autoimmunity mechanism associated with Gulf War Syndrome. James LM, Johnson RA, Lewis SM, et al. Lupus anticoagulant in Gulf War Illness and autoimmune disorders: a common pathway toward autoimmunity. J Immunological Sci. 2021; 5: 14–18. Dave had published a […]

Thrombotic Microangiopathies Presentation Handout

Click for the handout for “von Willebrand Factor, Friend or Foe,” which George presented on Friday, April 21, and Friday, April 29, 2023.

Arterial Thrombosis

Age-adjusted D-dimer Cutoff

From Amberly Nunez: Hi George, I am curious to see if anyone is using the age-adjusted D-dimer cutoff for PE? I know this topic was discussed in 2014 and wanted to see if there has been a practice change since that time. We are using the STA Liatest D-Di and our ED physicians have asked […]

May 2023 Cheat Sheet

Hello, click here for your May 2023 Cheat Sheet, which will be delivered to you by push in a few days. Enjoy.

May 2023 Quick Question: DOACs

Our May 2023 Quick Question asks “Which DOAC is a direct thrombin inhibitor?” Please select your answer. If you would like to add a comment, please click Comments below.

Anticoagulant Therapy

April 2023 Quick Question: Prince Alexis

Our April 2023 Quick Question asked, “What was Russian Prince Alexis’s disorder? Our 41 participants chose: Hemophilia A [FVIII deficiency] 16 [39%] Hemophilia B [FIX deficiency] 15 [37%] Hemophilia C [FXI deficiency] 3 [7 %] Unknown 7 [17%] While the bodies of the Tsar, Tsarina, three daughters, and servants were exhumed in 1991, the remains […]

Bleeding Disorders

Concizumab: Anti-TFPI

On 4-17-2023, Novo Nordisk announced Health Canada’s approval of Alhemo®, their trademark for injectable concizumab, the first anti-tissue factor pathway inhibitor [TFPI] designed to prevent bleeds in Hemophilia A and B patients with inhibitors. The current Canadian approval supports relatively few Hemophilia B [Christmas disease] patients with inhibitors but generalization to Hemophilia A patients could […]

Bleeding Disorders

World Hemophilia Day April 17, 2023

Click here for the World Federation of Hemophilia on April 17, 2023, World Hemophilia Day. The theme this year is “Access for All: Prevention of bleeds as the global standard of care.” The call to action is to come together and advocate with local policymakers and governments for improved access to treatment and care with […]

Bleeding Disorders

March 2023 CAP Today: Over-transfusion

The March 2023 Issue of CAP Today offers an anecdotal study on over-transfusion. The data could be enhanced with a review of laboratory assays such as viscoelastometry that help direct the need for red cells, platelets, or component-based hemostasis control. If you have experience with coag-based transfusion monitoring, please comment.

Bleeding Disorders

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George Fritsma is a medical laboratory scientist, educator, and author. George is a member of the International Society on Thrombosis and Hemostasis, the International Society for Laboratory Hematology, and the American Society for Clinical Laboratory Science.

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