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Underfilled Citrate Tubes

Hi George. My name is Reynaldo Caparros. I know that it has been taught and drilled in our knowledge on how we should properly fill up blue tops. This has also resulted in numerous delays in patient care. My question is, are there any studies that have been done to check the possibility that short […]

Specimen Management

World Thrombosis Day Today, 10-13-25

Click here for World Thrombosis Day information.

Anticoagulation Therapy Review

Dr. Emmanuel Favaloro’s 2018 open access review article “Anticoagulation therapy in Australia” has received 10,000+ views! The article is available for free download at: https://lnkd.in/gfcsyW5s. If you prefer the updated version published in JCM in 2025, during and post COVID-19, then head to https://lnkd.in/gAnPWn_E for a free download.

Anticoagulant Therapy

An Experimental Oral FVIII Mimetic

Click here in Hemostasis Today for a brief discussion of a developing phase 1 oral FVIII mimetic: Wolfgang Miesbach: Jan Astermark at the BIC 2025 presented Potentially the First Oral FVIII Mimetic Treatment for Hemophilia A.

Bleeding Disorders

October 2025 Cheat Sheet

Click here to read your October 2025 Fritsma Factor Cheat Sheet. Your personal copy will arrive soon in your inbox. If you aren’t receiving the “push” Cheat Sheet, please complete the form on the right. While you’re there, please give your answer to this month’s Quick Question. Both the Cheat Sheet and Fritsma Factor are […]

October 2025 QQ: Reporting Assay Uncertainty Data

Please refer to our August 29, 2025 discussion, “Hemostasis Assay Statistical Variation.” In this post, we linked the article, Mullier F, Gouin-Thibault I, Meijer P, et al. Time to integrate measurement uncertainty in method comparison and interpretation of hemostasis laboratory assays. Res Practice Thromb Hemost 2025: 9, https://doi.org/10.1016/j.rpth.2025.102993. The authors contend that we should report uncertainty […]

Quick Question Archive

September 2025 QQ: Viscoelastometry Discussion

Our September 2025 Quick Question asked, “What viscoelastometry device is employed at your facility?” A modest group of thirteen participants answered… TEG 6s: 4 (31%) TEG 5000: 2 (15%) ROTEM: 5 (39%) Sonoclot: 0 Hemosonics Quantra: 2 (15%) The TEG 5000 was developed in 1948, and the Sonoclot in 1975; both represent the pioneering phase […]

Quick Question Archive

Estrogen and Progesterone

Here is a question from my (Geo) friend and colleague, Kathryn Doig, MLS, PhD: “We all know that some women are prone to clots with both birth control hormones and menopausal hormones, but I want to understand why. I found a good review article with a reference (I have since lost) that showed an increase […]

Incubation to Inactivate Efanesoctocog Alfa Prior to Inhibitor Bethesda Titer

Click here for an open-access letter that indicates the need to inactivate plasma EHL FVIII efanesoctocog alfa (Altuuviiio®; Altuvoct®) before performing a Bethesda titer to measure anti-FVIII inhibitor: Bowyer A. Is incubation for 30 minutes at 56°C sufficient to fully inactivate efanesoctocog alfa? Haemophilia. 2025. doi: 10.1111/hae.70137. PMID: 40985057. The findings provide a recommended incubation […]

Bleeding Disorders

Does Chewing Gum Affect Fasting Blood Specimens?

On September 23, 2025, friend and colleague Dave McGlasson had a fasting blood specimen drawn. The collector noted that he was chewing gum and explained that the gum, although sugar-free, could affect the results. McGlasson messaged, “Chewing sugar-free gum should be avoided before a fasting blood draw because it can elevate certain blood levels, including […]

Specimen Management

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George Fritsma is a medical laboratory scientist, educator, and author. George is a member of the International Society on Thrombosis and Hemostasis, the International Society for Laboratory Hematology, and the American Society for Clinical Laboratory Science.

Cheat Sheets from George

Quick Question