Unexpected DRVVT Confirmation Results

I had the pleasure of meeting Norbert Bennattar, Directeur General of Cryopep, Montpellier, France while attending the International Society on Thrombosis and Haemostasis biennial meeting in Amsterdam, July 1–4, 2013. Mr. Bennattar posed a question I couldn’t answer. When performing the dilute Russell viper venom time (DRVVT) assay for lupus anticoagulant (LA), the operator begins with a screening assay. When prolonged […]

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Thrombophilia

Jul 16 2013

george

Mayo Medical Labs Conference August 7–9, 2013

Please join George in his Fritsma Factor booth at the Mayo Medical Laboratories’ 15th Bleeding and Thrombosing Disease Conference, Wednesday, August 7–Friday, August 9, 2013 at the Kahler Grand Hotel in Rochester, Minnesota. Once again we will offer meeting participant drawings for copies of Rodak BF, Fritsma GA, Keohane E, Hemostasis; Clinical Principles and Applications Fourth Edition, […]

Events

Quest Symposium, Oct 4–5, 2013

Quest, Inc announces its 6th Annual Case-Oriented Symposium on Bleeding and Thrombosis: A laboratory to bedside approach, Friday, October 4, and Saturday, October 5, 2013 at the Hilton McLean Tysons Corner in McLean, Virginia. The Quest Symposium has grown to be one of the premier events in hemostasis. Attached below is the complete program brochure and registration […]

Events

POC Screening for Coumadin Effect

From John McClure: We have been approached by our neurology and ER services to establish point of care prothrombin time/international normalized ratio (PT/INR) testing to assess for Coumadin effect prior to initiating thrombolytic therapy in stroke patients. One of our point of care (POC) coordinators has pointed out that the devices are FDA approved for monitoring […]

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Anticoagulant Therapy

Jul 2 2013

george

In-house Dilute TT

Dear George, I greatly appreciate your website and congratulate you on have such a informative and open educational forum. I was wondering if it was possible to add “in-house dilute thrombin time” to the current Quick Question list? Thank you for your consideration. Sincerely, Glen Holloway. Hello, Glen, and thank you for your suggestion. I will […]

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Anticoagulant Therapy

Jun 30 2013

george

Transient Recurrent FVII Deficiency?

Another from Linda Stang, Alberta Health Service: We have a patient with ‘transient, recurrent’ factor VII deficiency that I suspect is drug related. When FVII is low, protein C and factor X are normal. Patient has been as high as 1.57 u/mL and as low as 0.08 u/mL. Do you or any of your participants have […]

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Anticoagulant Therapy

Jun 14 2013

george

Some Significant Retirements

This post is not directly related to hemostasis, but I want to highlight the retirements of three esteemed colleagues, Bernadette F. (Bunny) Rodak, MS MT (ASCP) SH, Professor of the Clinical Laboratory Science Program, Jacqueline H. Carr, MS MT (ASCP) Laboratory Manager, Department of Pathology and Laboratory Medicine, both at Indiana University Health in Indianapolis; and Carol McCoy, PhD, […]

Events

Adjust Citrate in Severe Anemia?

From Barbara Caufield, Good Samaritan Hospital: We adjust the Na citrate volumes in coagulation tubes when the hematocrit (HCT) is > 55%. Do you recommend correcting for low HCTs? Can you tell me what formula you would use for a low HCT? At what HCT percentage do you recommend adjusting the sodium citrate? Thank you! Hello, Barbara, […]

Specimen Management

Sodium Citrate: 3.8%?

A contributor asks, “has sb reported shorter clotting times when using 3.8% (0.129M) sodium citrate tubes than 3.2% (0.109M) tubes? literature and the logic says the opposite.” Hello, and thank you for your question. I’m unsure of your reference to “sb,” however I agree that it is logical to presume that the 3.8% sodium citrate […]

Screening Assays

Pradaxa Measurement: An Oxymoron?

George sent this message to Dr. David Alter, Spectrum Health System, Grand Rapids, Michigan (once named Butterworth Hospital), regarding a question he posted on MEDLAB-L on Monday, June 10, asking, “Isn’t monitoring Pradaxa an oxymoron?”: “Hi, Dr. Alter. I subscribe to MEDLAB-L and just saw your post regarding Pradaxa measurement. May I post your question and some discussion […]

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Anticoagulant Therapy

All Posts

Unexpected DRVVT Confirmation Results

Mayo Medical Labs Conference August 7–9, 2013

Quest Symposium, Oct 4–5, 2013

POC Screening for Coumadin Effect

In-house Dilute TT

Transient Recurrent FVII Deficiency?

Some Significant Retirements

Adjust Citrate in Severe Anemia?

Sodium Citrate: 3.8%?

Pradaxa Measurement: An Oxymoron?

George Fritsma MS MLS

Cheat Sheets from George

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