Back to the ELT

In follow-up to Cassandra McGeachy’s August 7 question on the euglobulin lysis time (ELT), I’ve found two references for upgraded ELT methods that may be helpful.They are: Cellai AP. Lami D, Magi A, et al. Assessment of fibrinolytic activity by measuring the lysis time of a tissue factor-induced clot: a feasibility evaluation. Clin Appl Thromb Hemost 2010;16:337–44. […]

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Fibrinolysis

Aug 15 2014

george

Honolulu Oct 21–22

George presents “Monitoring the New Anticoagulants, Whatever Happened to the PT and PTT?” and “Managing Trauma-induced Coagulopathy,” for the 2014 ASCLS-HI Clinical Laboratory Symposium Update at the Ko’olan Conference Center near Honolulu, Hawaii, October 21 and 22 (well, someone has to do it!). Times for George’s talks are to be announced. We hope you can […]

Events

Mayo Conference Sept 10–12

You are invited to the Clinical and Laboratory Update in Thrombosis, Anticoagulation and Vascular Medicine: A Board Review Primer, this fall’s Mayo School of Continuous Professional Development at the Mayo Civic Center, Rochester, Minnesota. This is a new location for the meeting, and you will find both The Fritsma Factor and Precision BioLogic represented in the […]

Events

Drawing Above Heparin Line

We avoid collecting blood from an arm that has an intravenous line, however this practice seems to rely on conventional wisdom, not data. Here is a question from Dennis Ernst, Center for Phlebotomy Education about collecting above a heparin line: My CLSI committee is revising the venipuncture standard and is having trouble locating anything new on drawing above […]

Specimen Management

Euglobulin Lysis Time

From friend and colleague Cassandra McGeachy, Louisiana Coagulation Laboratory, Hi George, I am looking for procedures available for performing the euglobulin lysis time (ELT). I am looking to update my present method if there are any options available. Hello, Cassy, and thank you for your question. At first I was going to suggest you just discontinue the […]

Fibrinolysis

Ebola Precautions

George presented the first part of a three-part AACC webinar series, Quality Assurance in Hemostasis; What Makes Us Different? A question arose about Ebola virus specimen management. Though not specifically related to hemostasis, it seems appropriate to provide a link to the US Centers for Disease Control and Prevention (CDC) specimen precautions. What the CDC document […]

Specimen Management

Factor VII Padua Mutation

As a followup to the July 30 Discordant PT Results, George presented this problem to a colleague in the booth of one of the major hemostasis materials distributors in the Clinical Laboratory Expo, thereby “spoiling his day.” Nevertheless, he had the answer by days’ end, confirming the response posted by Dr. Vadim Kostousov. This was further confirmed […]

Screening Assays

AACC “Quick Takes” on Quality Assurance

Join George as he kicks off the American Association of Clinical Chemists (AACC) Quick Takes webinar series with “Quick Takes on Quality Assurance in Hemostasis.” George will present three 30-minute presentations on August 7, 14, and 21, 1–1:30 EDT. He will discuss: Employing local calibration for prothrombin time/international normalized ratio (PT/INR) monitoring of Coumadin therapy. Specimen management […]

Events

Discordant PT Results

George is attending the annual AACC meeting at McCormick Place in Chicago. A colleague described a puzzling case in which a patient has a prolonged prothrombin time (PT) using a 1.3 ISI thromboplastin reagent (Stago) and a normal PT when using Dade (Siemens) Innovin. The findings are consistent on repeat split specimens, the PTT is […]

Screening Assays

Bleeding in 75-YO With CLL

Here is a case sent in by a colleague. A 75 YO woman with CLL. In April, 2014, she had a prolonged PTT but was not worked up. She recently presented to an outside hospital with weakness and falls and was found to have a HGB of 5.1 g/dL and a PTT of 90 seconds. […]

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Coagulation Factors

All Posts

Back to the ELT

Honolulu Oct 21–22

Mayo Conference Sept 10–12

Drawing Above Heparin Line

Euglobulin Lysis Time

Ebola Precautions

Factor VII Padua Mutation

AACC “Quick Takes” on Quality Assurance

Discordant PT Results

Bleeding in 75-YO With CLL

George Fritsma MS MLS

Cheat Sheets from George

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