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Oct 1 2026
george

October 2026 QQ: Which is NOT an APL?

Our October 2026 Quick Question is a quiz that asks, “Which is NOT an antiphospholipid antibody?” The choices are…  Anti beta-2 glycoprotein 1  Alpha-2 antiplasmin  Lupus anticoagulant  Antiprothrombin  Anticardiolipin Antiphospholipid antibodies are acquired autoantibodies that bind phospholipid-bound proteins. Please go to the question on the right of your screen, make your selection, and add your […]
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Blog
Oct 1 2026
george

July 2026 CAP Today Q & A Column: Lipoprotein (a).

Q. Our providers pointed out that lipoprotein(a) results from different laboratories are discordant, so they asked us to bring the assay in-house. Is this a good idea? A. Lipoprotein(a), or Lp(a), is a prothrombotic, proinflammatory, and atherogenic cholesterol-rich particle. Plasma concentration of Lp(a) is an important genetic determinant of atherosclerotic cardiovascular disease (ASCVD) risk, and […]
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Thrombophilia
Sep 30 2026
george

A Summary of VWD Management by Dr. Favaloro

See this open-access editorial summarizing current VWD diagnosis and management. Favaloro EJ. 100 years of von Willebrand disease: celebrating a significant milestone in von Willebrand disease diagnostics and management. Semin Thromb Hemost. 2026;52(7):762-764. doi: 10.1055/a-2877-9583. PMID: 42190737. Further, here’s a link to the entire Seminars in Thrombosis and Hemostasis, October 2026, that addresses Hemostasis in […]
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Bleeding Disorders
Sep 28 2026
george

Review: Pediatric VTE

While we focus on arterial and venous thrombosis, October 13 is the official World Thrombosis Day. With this thought in mind, here is a richly illustrated review describing pediatric VTE: Espanol MG, Janbain M. Pediatric venous thromboembolism: an illustrated review. Res Pract Thromb Haemost. 2026;10:106892. doi: 10.1016/j.rpth.2026.106892. PMID: 42699084; PMCID: PMC13543900. Abstract Venous thromboembolism (VTE) […]
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Thrombophilia
Sep 16 2026
george

Heparin Re-exposure in HIT Patients

Obtain this article about HIT from your local medical library: Caudill EB, Kim JH, Kanaan DM, Sylvester KW, Pimentel LY, Kim CS, Connors JM. Heparin re-exposure in patients with a history of heparin-induced thrombocytopenia. J Thromb Haemost. 2026 Aug 3:S1538-7836(26)00484-8. doi: 10.1016/j.jtha.2026.07.024. PMID: 42546848. Objective To evaluate heparin re-exposure practices and safety in patients with […]
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Anticoagulant Therapy
Sep 8 2026
george

Can AI Replace Clinical Prediction Scores in Thrombophilia?

Here is an open-access that compares the efficacy of AI with traditional clinical prediction scores for thrombophilia: Danilatou V, Arachchillage DJ. Beyond accuracy: why replacing traditional scores with AI in thrombosis care creates new ethical and regulatory obligations. Semin Thromb Hemost. 2026 Sep 3. doi: 10.1055/a-2943-7750. PMID: 42692078. Abstract Clinical prediction scores have been central […]
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Thrombophilia
Sep 8 2026
george

Study Results: Novel Thrombin Generation Assay Monitors Emicizumab and Octocog Alfa

Here are the open-access results of a study testing the efficacy of a novel intrinsic trigger reagent (platelet-poor plasma [PPP] Reagent INT) for monitoring emicizumab and octocog alfa: Urlings EH, Heubel-Moenen FCJI, van Oerle R, et al. Intrinsic activated thrombin generation for treatment efficacy and monitoring of octocog alfa and emicizumab in severe hemophilia A. […]
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Bleeding Disorders
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George Fritsma MS MLS

George Fritsma is a medical laboratory scientist, educator, and author. George  is a member of the International Society on Thrombosis and Hemostasis, the International Society for Laboratory Hematology, and the American Society for Clinical Laboratory Science.

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Quick Question

Which is NOT an antiphospholipid antibody?