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Aug 16 2025
george

July 2025 CAP Today: A Deep Dive Into Key Hemostasis Testing Variables

Click A Deep Dive Into Key Hemostasis Testing Variables for an in-depth review of preanalytical hemostasis specimen concerns. The CAP article features Andrew Goodwin MD, professor, Department of Pathology and Laboratory Medicine, University of Vermont Larner College of Medicine, and medical director of the thrombosis and hemostasis section, University of Vermont Medical Center; and Dr. […]
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Specimen Management
Jul 29 2025
george

July 2025 QQ: Hemophilia Rebalancing Therapy

Our July 2025 Quick Question asked, “Which is a hemophilia ‘rebalancing’ therapeutic?” The question attracted a modest 22 participants, perhaps an indication that rebalancing therapy was only FDA-approved in 2025 and awaits approval in Canada and Europe. Here are your responses… Valoctocogene roxaparvovec-rvox (ROCTAVIAN) 3 (14%) Efanesoctocog alfa (ALTUVIIIO) 1 (4%) Emicizumab (HemLibra) 7 (32%) […]
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Quick Question Archive
Jul 23 2025
george

Anti-Xa DOAC Assay Variability

Click here to read an open-access article describing the variability in assay methodology when monitoring apixaban and rivaroxaban: Baker RM, Selby R, Moffat KA, St John M, Spyropoulos AC, Schulman S, Douketis J. Investigating interassay variability between direct oral anticoagulant calibrated anti-factor Xa assays: a substudy of the perioperative anticoagulation use for surgery evaluation (PAUSE) […]
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Anticoagulant Therapy
Jul 22 2025
george

Autoimmune Acquired Coagulation Factor Deficiencies

Click here for the open-access review of Ichinose A, Osaki T, Souri M. Diagnosis and treatment of autoimmune acquired coagulation factor deficiencies: an evidence-based review of Japanese practice. Semin Thromb Hemost. 2025;51:491-505. doi: 10.1055/s-0044-1787188. Epub 2024 Jun 12. PMID: 38866039. Abstract Among the acquired coagulation factor deficiencies, autoimmune coagulation factor deficiencies (AiCFD) are rare and […]
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Bleeding Disorders
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George Fritsma MS MLS

George Fritsma is a medical laboratory scientist, educator, and author. George  is a member of the International Society on Thrombosis and Hemostasis, the International Society for Laboratory Hematology, and the American Society for Clinical Laboratory Science.

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Quick Question

What AC does your provider prescribe for non-valvular AFIB?