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Bioengineered FVIII: efanestocog alfa

Here is a richly illustrated open-access editorial of the development and physiologic function of efanesoctocog alfa (Altuviiio®, Sanofi), which features a half-life 4X that of current concentrates: Chowdary P. Bioengineered factor VIII–more innovation for Hemophilia A. N Engl J Med. 2024;391:277–82. doi: 10.1056/NEJMe2313795. PMID: 39018538.
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