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Initialisms with their Definitions

Abbreviations

  • β2GP1: β2 glycoprotein 1
  • 11DOHTXB2: 11-dehydrothromboxane B2
  • 11DOH: 11-dehydrothromboxane B2
  • AABB: Association for the Advancement of Blood & Biotherapies (formerly American Association of Blood Banks)
  • ABR: Annual Bleed Rate
  • ACA: Anti-cardiolipin antibody (also ACL)
  • ACL: Anti-cardiolipin antibody (also ACA)
  • ACT: Activated clotting time assay
  • ADAMTS13: A disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (also VWF-cleaving protease)
  • ADLM: Association for Diagnostics and Laboratory Medicine (formerly AACC)
  • ADP: Adenosine diphosphate
  • AF: Atrial fibrillation
  • AFIB: Atrial fibrillation
  • AMI: Acute myocardial infarction
  • anti-Xa: Chromogenic anti-Xa anticoagulant assay (heparin and anti-Xa DOACs)
  • API: American Proficiency Institute, provides external quality assurance services
  • APC: Activated protein C
  • APCR: Activated protein C resistance
  • APL: Anti-phospholipid antibody
  • APTT: Activated partial thromboplastin time, partial thromboplastin time (PTT)
  • ARU: Aspirin resistance unit
  • ASA: Aspirin; acetyl salicylic acid
  • ASCLS: American Society for Clinical Laboratory Science
  • AT: Antithrombin or antithrombin III (obsolete)
  • ATIII: Antithrombin III (obsolete) or antithrombin
  • ATP: Adenosine triphosphate
  • BDD: B-domain-deleted (factor concentrate)
  • BMJ: British Medical Journal
  • BSS: Bernard-Soulier syndrome
  • BT: Bleeding time (obsolete)
  • BU: Bethesda units
  • CABG: Coronary artery bypass graft
  • CAP: The College of American Pathologists, provides external quality assurance services
  • CAPS: Catastrophic antiphospholipid syndrome
  • CBC: Complete blood count
  • CDC: US Centers for Disease Control and Prevention
  • CFX: Chromogenic factor X Assay (warfarin assay)
  • CLIA: Clinical Laboratory Improvement Amendments
  • CLIAC: Clinical Laboratory Improvement Advisory Committee
  • CLL: Chronic lymphocytic leukemia
  • CLSI: Clinical and Laboratory Standards Institute
  • COX: Cyclooxygenase
  • COX-1: cyclooxygenase-1
  • COX-2: cyclooxygenase-2
  • CRP: C-reactive protein, an inflammation marker
  • CSA: Two-stage chromogenic substrate factor assay
  • CVA: Cerebrovascular accident (stroke)
  • D-D: D-dimer
  • DAPT: dual antiplatelet therapy
  • DDAVP: Desamino-8-D-arginine vasopressin, desmopressin
  • DIC: Disseminated intravascular coagulation
  • DOAC: Direct oral anticoagulant therapeutic
  • DRVVT: Dilute Russell viper venom time
  • DTI: Direct thrombin inhibitor
  • DTS: Dense tubular system
  • DVT: Deep venous thrombosis
  • EC: Endothelial cell
  • ECA: Stago’s Ecarin Chromogenic Assay
  • ECAT: European Concerted Action on Thrombosis (ECAT Foundation), provides External Quality Assessment Programme (EQAP)
  • ECMO: Extra-corporeal membrane oxygenation
  • ECT: Ecarin clotting time
  • ED: Emergency department, emergency room
  • EHL: Extended half-life (factor concentrate)
  • EIA: Enzyme immunoassay
  • ELISA: Enzyme-linked immunosorbent assay
  • ELT: Euglobulin lysis time
  • EQAP: External Quality Assessment Programme
  • ER: Emergency room, emergency department
  • EUA: FDA emergency use authorization
  • ESRD: End-stage renal disease
  • FB: Fibroblast
  • FBG: Fibrinogen (also Fg)
  • Fc: The “fragment crystallizable” antibody region that interacts with cell surface receptors called Fc receptors
  • FDA: US Food and Drug Administration
  • FDP: Fibrin (ogen) degradation products
  • FEIBA: Factor VIII inhibitor bypassing activity
  • FFP: Fresh frozen plasma
  • Fg: Fibrinogen (also FBG)
  • FIX: Coagulation factor IX
  • FP24: 24-hour frozen plasma
  • FRET: Fluorescence resonance energy transfer
  • FSP: Fibrin (ogen) split products (also FDP, fibrin degradation products)
  • FVIII: Coagulation factor VIII
  • FVIII:C: Factor VIII coagulant activity
  • FVIIIR:Ag: Factor VIII-related antigen
  • FVL: Factor V Leiden mutation
  • g/dL: Grams per deciliter
  • GP Ib: Glycoprotein Ib
  • GP IIb: Glycoprotein IIb
  • GP IIb/IIIa: Glycoprotein IIb/IIIa
  • GP IX: Glycoprotein IX
  • GP V: Glycoprotein V
  • GT: Glanzmann thrombasthenia
  • HA: Hemophilia A (FVIII deficiency)
  • HB: Hemophilia B (FIX deficiency)
  • Hb: hemoglobin (HGB)
  • HCT: Hematocrit
  • HCY: Homocysteine
  • HGB: Hemoglobin (Hb)
  • HIT: Heparin-induced thrombocytopenia with thrombosis
  • HITT: Heparin-induced thrombocytopenia with thrombosis
  • HMWK: High molecular weight kininogen (Fitzgerald factor)
  • HPA: Human platelet antigen
  • HRT: Hormone replacement therapy
  • HUS: Hemolytic-uremic syndrome
  • Hx: History
  • ICH: Intracranial hemorrhage
  • ICSH: International Council for Standardization in Haematology
  • IFU: Instructions for use
  • IJLH: International Journal of Laboratory Hematology
  • IL: Interleukin
  • IM: Intramuscular
  • INR: International normalized ratio
  • IPA: Isopropyl alcohol
  • IRP: International reference preparation
  • ISI: International sensitivity index
  • ISLH: International Society for Laboratory Hematology
  • ISTH: International Society on Thrombosis and Haemostasis
  • ITP: Immune thrombocytopenic purpura
  • IV: Intravascular
  • IVD: In vitro diagnostics
  • IVIg: Intravenous immunoglobulin
  • JACC: Journal of the American College of Cardiology
  • LA: Lupus anticoagulant
  • LAC: Lupus anticoagulant
  • LDT: Lab-developed test
  • LIA: Latex immunoassay
  • LMWH: Low molecular weight heparin
  • LVAD: Left ventricular assist device
  • mg/dL: Milligrams per deciliter
  • MNPT: Mean normal prothrombin time
  • MPN: Myeloproliferative neoplasm
  • MRI: Mean of the reference interval
  • NASCOLA: North American Specialized Coagulation Laboratory Association
  • NATP: Neonatal alloimmune thrombocytopenic purpura
  • ng/mL: Nanograms per milliliter
  • NBU: Nijmegen Bethesda unit
  • NO: Nitric oxide
  • NP: Normal plasma
  • NSAID: Non-steroidal anti-inflammatory drug
  • NVAF: Non-valvular atrial fibrillation
  • OC: Oral contraceptive
  • OAC: Oral anticoagulant
  • OCR: Oral contraceptive
  • OCS: Open canalicular system
  • OSA: One-stage clot-based factor assay
  • PAD: Peripheral artery disease, peripheral artery occlusion
  • PAI-1: Plasminogen activator inhibitor-1
  • PAO: Peripheral artery occlusion, peripheral artery disease
  • PC: Protein C
  • PCC: Prothrombin complex concentrate
  • PCI: Percutaneous coronary intervention
  • PCR: Polymerase chain reaction
  • PE: Pulmonary embolism
  • PECAM: Platelet-endothelial cell adhesion molecule
  • PF 1+2: Prothrombin fragment 1+2
  • PF 1.2: Prothrombin fragment 1.2
  • PF4: Platelet factor 4
  • PFA: Platelet function analyzer
  • PFP: Platelet-free plasma
  • PG: Prostaglandin
  • PITT: Anti-PF4 mediated thrombocytopenia and thrombosis
  • PIVKA: Proteins in vitamin K antagonism
  • PK: Prekallikrein (Fletcher factor) or pharmacokinetics
  • PL: Phospholipid
  • PLA: Human platelet antigen
  • PLC: Phospholipase C
  • PLT: Platelet
  • PNP: Pooled normal plasma
  • POC: Point of care
  • PPP: Platelet-poor plasma
  • PRP: Platelet-rich plasma
  • PS: Protein S
  • PT: Prothrombin time (protime)
  • PT/INR: Prothrombin time with international normalized ratio
  • PTR: Prothrombin time ratio
  • PTT: partial thromboplastin time, activated partial thromboplastin time
  • RBC: Red blood cell
  • RI: Reference interval, “normal range”
  • RIPA: Ristocetin-induced platelet aggregation
  • RNA: Ribonucleic acid
  • ROC: Receiver-operating characteristic
  • ROTEM: Rotational thromboelastometry
  • RUO: Research use only
  • RVVT: Russell viper venom time
  • Rx: Prescription, therapeutic
  • SAK: Staphylokinase
  • SC: Subcutaneous, subcutaneously
  • SERPIN: Serine protease inhibitor
  • SIC: Sepsis-induced coagulopathy
  • SK: Streptokinase
  • SMC: Smooth muscle cell
  • SOFA: Sequential organ failure assessment
  • SOP: Standard operating protocol (procedure)
  • SPRCA: Solid-phase red blood cell agglutination assay
  • STH: Seminars in Thrombosis and Hemostasis
  • SQ: Subcutaneous
  • TAFI: Thrombin-activated fibrinolysis inhibitor
  • TAT: Thrombin-antithrombin
  • TCT: Thrombin clotting time
  • TEG: Thromboelastograph, thromboelastography
  • TEM: Rotational thromboelastometry
  • TF: Tissue factor
  • TIA: Transient ischemic attack
  • TM: Thrombomodulin
  • TMA: Thrombotic microangiopathy
  • TNF: Tumor necrosis factor
  • TPA: Tissue plasminogen activator
  • TT: Thrombin clotting time
  • TTI: Tissue thromboplastin inhibition
  • TTP: Thrombotic thrombocytopenic purpura
  • TTR: Time in therapeutic range
  • TXA2: Thromboxane A2
  • TXB2: Thromboxane B2
  • UA: Unstable angina
  • UFH: Unfractionated (standard) heparin
  • UK: Urokinase
  • USPI: United States Prescribing Information
  • VET: Viscoelastometry (thromboelastometry)
  • VITT: Vaccine-induced immune thrombotic thrombocytopenia
  • VK: Vitamin K
  • VKA: Vitamin K antagonist
  • VTE: Venous thromboembolism
  • VWD: von Willebrand disease
  • VWF: von Willebrand factor
  • VWF:Act: von Willebrand factor activity
  • VWF:Ag: von Willebrand factor antigen
  • VWF:CB: von Willebrand factor collagen binding activity
  • VWFCP: von Willebrand factor cleaving protease (ADAMTS13)
  • VWF:Gp1bR: Ristocetin-triggered nonplatelet GPIb-based activity assay
  • VWF:Gp1bM: Gain-of-function high-affinity recombinant GPIb-based activity assay
  • VWF:RCo: von Willebrand factor ristocetin cofactor activity
  • WBC: White blood cell
  • YO: year-old, years of age
  • YOA: Years of age