World Thrombosis Day Today, 10-13-25

Click here for World Thrombosis Day information.

Sep 29 2025

Estrogen and Progesterone

Here is a question from my (Geo) friend and colleague, Kathryn Doig, MLS, PhD: “We all know that some women are prone to clots with both birth control hormones and menopausal hormones, but I want to understand why. I found a good review article with a reference (I have since lost) that showed an increase […]

Thrombophilia

A Relationship Between Radiotherapy and Venous Thrombosis

Click here for an open-access 2025 article that describes the relationship between radiotherapy and cancer-associated venous thrombosis: Gurumurthy G, Miller J, Carrier M, Khorana A, Thachil J. Radiotherapy-the not-so-insignificant contributor to cancer-associated venous thrombosis. Res Pract Thromb Haemost. 2025;9:102985. doi: 10.1016/j.rpth.2025.102985. PMID: 40837025; PMCID: PMC12362088. Abstract Venous thromboembolism is a well-established complication in patients with […]

Thrombophilia

APL Positivity Cutoffs: 99th Percentile?

For a fresh look at anticardiolipin antibody and anti-β2-GP1 analysis decision points, click Anunciación-Llunell A, Marques-Soares J, Ockova M, et al. The absence of standardization in antiphospholipid antibody testing may favor the use of 99th percentile cutoffs in antiphospholipid syndrome classification. Res Pract Thromb Haemost. 2025;9:102967. doi: 10.1016/j.rpth.2025.102967. PMID: 40761700; PMCID: PMC12320162.

Thrombophilia

World Thrombosis Day Campaign: Note From Samantha Nelson, WTD Manager

Dear George, The International Society on Thrombosis and Haemostasis (ISTH) World Thrombosis Day (WTD) campaign is in its 12th year, and together with The Fritsma Factor, Your Interactive Hemostasis Resource, we have been working to build awareness around a critical reality: 1 in 4 people worldwide die each year from conditions related to thrombosis. This […]

Thrombophilia

World Thrombosis Day 2025

It’s time to be thinking about World Thrombosis Day. From the WTD site, “World Thrombosis Day, founded by the International Society on Thrombosis and Haemostasis (ISTH), is a global initiative held annually on October 13. Our mission is to raise awareness about thrombosis, a condition often underestimated and misunderstood. Your participation can help inspire positive […]

Thrombophilia

Thrombotic Thrombocytopenic Purpura

Click “In Their Blood” for a review article about TTP from the University of Kansas (KU) Medical Center’s Pathology Department. The article highlights the early research into ADAMTS13‘s role in VWF metabolism, the early successes of PLEX therapy, and the current availability of the therapeutics caplacizumab and the ADAMTS13 concentrate, Adzynma. Also featured is the […]

Bleeding Disorders

August 2025 QQ: Anticoagulant Choice for AFIB

Our August 2025 Quick Question asks, “What AC does your provider prescribe for non-valvular AFIB?” I (Geo) asked my PCP this question at my annual wellness visit on July 29, 2025. Not a personal concern, just curious. Please provide your answer on the right and add your comments, which will appear in our end-of-month summary.

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Quick Question Archive

Jul 22 2025

george

Postpartum DIC

Check with your medical library for this review, dated 7-18-25. Wolfovitz A, Brenner B, Solt I. Postpartum disseminated intravascular coagulation: A comprehensive review of pathophysiology, diagnosis, management, and prevention. Semin Thromb Hemost. doi: 10.1055/a-2645-2845. Epub ahead of print. PMID: 40680793. Abstract Disseminated intravascular coagulation (DIC) in the postpartum period is a rare but potentially life-threatening […]

Fibrinolysis

What is Monoclonal Gammopathy of Thrombotic Significance?

Just when we thought there was nothing new in hemostasis, the June 2025 CAP Today front-page article by Karen Titus, Spectrum of Anti-PF4 Disorders Widens, ties together HITT, VITT, and what we have known as commonplace MGUS, here renamed MGTS, all fit together in the category, anti-PF4 disorders. I (Geo) recommend this excellent article that […]

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Thrombophilia

Thrombophilia

World Thrombosis Day Today, 10-13-25

Estrogen and Progesterone

A Relationship Between Radiotherapy and Venous Thrombosis

APL Positivity Cutoffs: 99th Percentile?

World Thrombosis Day Campaign: Note From Samantha Nelson, WTD Manager

World Thrombosis Day 2025

Thrombotic Thrombocytopenic Purpura

August 2025 QQ: Anticoagulant Choice for AFIB

Postpartum DIC

What is Monoclonal Gammopathy of Thrombotic Significance?

George Fritsma MS MLS

Cheat Sheets from George

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