A Coag Conversation: Alternate Warfarin Monitoring When the Prothrombin Time is Unreliable – Part 3: DOACs and Warfarin

Join me (Geo) and guest speaker Dr. Nicole Zantek, MD, PhD, Medical Director of the Special Coagulation Laboratory and Professor, Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, as we discuss the pathophysiology of antiphospholipid antibodies and alternative methods to monitor warfarin and DOAC anticoagulation in patients diagnosed with APS. Click DOACs […]

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Anticoagulant Therapy

Nov 26 2025

george

Response to Low PS Inquiry on Diverse Health Hub

This question was posted on the Diverse Health Hub site (AKA Diagnostic Equity): “Can my birth control pills explain why my protein S level is low at 55%? OR…. should I be evaluated for an actual clotting disorder since low protein S runs in my family?” This comprehensive response was provided by my colleague, LaShanta […]

Thrombophilia

Coag Conversation About Alternative Methods to Monitor Anticoagulant Therapy Part 2: Anticoagulation for Antiphospholipid Syndrome

Join me (Geo) and guest speaker Dr. Nicole Zantek, MD, PhD, Medical Director of the Special Coagulation Laboratory and Professor, Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, as we discuss the pathophysiology of antiphospholipid antibodies and alternative methods to monitor warfarin and DOAC anticoagulation in patients diagnosed with APS. Click Anticoagulation […]

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Anticoagulant Therapy

Nov 12 2025

george

Alternate Functions of AT, PC, PS, and TFPI

Go to your medical library to download the meta-analysis Prouse T, Mast AE, Ignjatovic V, Kovac M, Bereczky Z, Majumder R. Alternate functions of physiological anticoagulants. J Thromb Haemost. 2025:S1538-7836(25)00540-9. doi: 10.1016/j.jtha.2025.08.014. PMID: 40907701. Abstract The anticoagulant proteins antithrombin, protein C, protein S, and tissue factor pathway inhibitor are physiological regulators of the blood coagulation […]

Thrombophilia

Red Light Therapy in Hemostasis and Thrombosis

Check with your medical library for an advanced study of the effects of red light therapy upon hemostasis: Fan BE, Pasalic L, Hew YY, Lippi G, Favaloro EJ. Red light therapy in thrombosis and hemostasis. Semin Thromb Hemost. 2025. doi: 10.1055/a-2717-5157. Epub ahead of print. PMID: 41062078. Abstract Red light therapy is emerging as a […]

Antiplatelet Therapy

Analysis of Antiphospholipid Antibody Testing

Select an open-access article, Thirunavukarasu C, PasalicL, Favaloro EJ. A contemporary analysis of solid-phase antiphospholipid antibody testing: implications for classification or diagnosis of antiphospholipid syndrome, Pathology, https://doi.org/10.1016/j.pathol.2025.07.003 for a look at current ACL and anti β-2 glycoprotein 1 assays and their efficacy in diagnosing APS. Abstract Antiphospholipid antibody (aPL) testing is required for diagnosis of […]

Thrombophilia

Two Cases of Brown Recluse Envenomation

Here is an open-access article that describes cases that illustrate the coagulopathy associated with brown recluse spider bites. Hart SA, Gailani D, Bibb LA, et al. Coagulation abnormalities following brown recluse spider (Loxosceles reclusa) envenomation: A description of 2 cases and review of the literature. Am J Clin Pathol. 2025;163:822–36. doi: 10.1093/ajcp/aqaf001. PMID: 39883062; PMCID: […]

Thrombophilia

A Coag Conversation: Alternate Warfarin Monitoring When the Prothrombin Time is Unreliable – Part 1

Join me (Geo) and guest speaker Dr. Nicole Zantek, MD, PhD, Medical Director of the Special Coagulation Laboratory, Professor, Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, who discusses the pathophysiology of antiphospholipid antibodies, and alternative methods to monitor warfarin and DOAC anticoagulation in patients diagnosed with antiphospholipid syndrome. This is the […]

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Anticoagulant Therapy

Oct 25 2025

george

The Blood Project: TTP Module

Click here for a comprehensive review of TTP. This is a segment within The Blood Project, a not-for-profit organization committed to advancing medical knowledge about the crucial role of blood in human health, disease, and therapeutics. TBP offers open-access, web-based, and expertly curated learning tools and resources with the following goals: Enhance Hematological Knowledge: TBP […]

Thrombophilia

A Coag Conversation: Alternate Warfarin Monitoring When the Prothrombin Time is Unreliable – Part 3: DOACs and Warfarin

Response to Low PS Inquiry on Diverse Health Hub

Coag Conversation About Alternative Methods to Monitor Anticoagulant Therapy Part 2: Anticoagulation for Antiphospholipid Syndrome

Alternate Functions of AT, PC, PS, and TFPI

Red Light Therapy in Hemostasis and Thrombosis

Analysis of Antiphospholipid Antibody Testing

Two Cases of Brown Recluse Envenomation

A Coag Conversation: Alternate Warfarin Monitoring When the Prothrombin Time is Unreliable – Part 1

The Blood Project: TTP Module

World Thrombosis Day Today, 10-13-25

George Fritsma MS MLS

Cheat Sheets from George

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