Intermountain States Seminar 10-18-20

The Intermountain States Seminar [IMSS, click] has assembled each fall in Jackson, Wyoming, but this year it is a virtual event planned for Sunday, October 18–Tuesday, October 20. George presents, “Covid-associated Coagulopathy: Controversies and Confusion” on Sunday, October 18, 3:30–4:30 Mountain Time. The topic is an expansion of our September 15, 2020 webinar, a dialogue […]

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Events

Oct 1 2020

george

October 2020 Quick Question: Inflammation

Our October Quick Question is selected from the many open questions we received during our September 15 webinar. “Covid-Associated Coagulopathy: A Conversation about Controversies and Confusion” [click] featuring Andrew Goodwin, MD, CLIA Medical Director, University of Vermont Medical Center and Laboratory Services and Section Medical Director of the Thrombosis and Hemostasis Laboratory. In our Quick […]

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Quick Question Archive

Sep 26 2020

george

Covid-Coag Conversation Video

Thanks to all who participated in our September 15, 2020 webinar, “COVID-Associated Coagulopathy: A Conversation about the Controversies & Confusion” [click] featuring Dr. Andrew Goodwin, University of Vermont Medical Center. Click the title line if you would like to view the webinar again or if you did not have the opportunity to attend the live […]

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Anticoagulant Therapy

Sep 14 2020

george

Covid-Coag Conversation 9-15-20: Reminder

Reminder: You are invited to our Tuesday, tomorrow, September 15, 2020 webinar, Covid-Associated Coagulopathy: A Conversation about the Controversies and Confusion featuring pathology expert Andrew J. Goodwin, MD, University of Vermont Medical Center Laboratory Director. Click https://conta.cc/3aMDoNp for the eblast or bit.ly/COVID-Coag to go directly to the registration page. Covid-Coag is a PACE-accredited one-hour presentation, […]

Events

August, 2020 Quick Question on D-dimer Results

Our August, 2020 Quick Question asks, “What condition may account for a chronically elevated D-dimer?” We’ve had 59 respondents with a broad distribution of results: Plasma human anti-mouse antibody: 7% [4] Rheumatoid factor: 14% [8] Chronic low-grade inflammation: 24% [14] Venous thromboembolic disease: 17% [10] Disseminated intravascular coagulation: 34% [20] Other, please comment: 4% [3] […]

Fibrinolysis

Covid-Coag Conversation 9-15-20

You are invited to our Tuesday, September 15, 2020 webinar, Covid-Associated Coagulopathy: A Conversation about the Controversies and Confusion featuring pathology expert Andrew J. Goodwin, MD, University of Vermont Medical Center Laboratory Director. Click https://conta.cc/3aMDoNp for the eblast or bit.ly/COVID-Coag to go directly to the registration page. Covid-Coag is a PACE-accredited one-hour presentation, 5–6 PM […]

Arterial Thrombosis

Mixing Studies

A note from colleague Kathy Robinson that deserves a thorough discussion… “I am updating our mixing study procedure and have some questions…” 1. What is the lower limit at which it is useless to perform studies for both PT & PTT [APTT]? There is no firm agreement about the limit. Some perform mixes whenever the […]

Bleeding Disorders

Case: Consistent D-dimer Elevation

A 35-YO woman experiences fatigue. The attached table [click] illustrates typical laboratory findings consistent over 18 months: reduced MCV, MCH, and MCHC, and mildly elevated ESR, CRP, and D-dimer. She reports that she has sickle-thalassemia, which accounts for her slightly decreased RBC indices. Please refer to our August Quick Question on the right, and choose […]

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Quick Question Archive

Jul 31 2020

george

July, 2020 Quick Question on Covid Coag Results

Our July, 2020 Quick Question, “What assay does your lab use to monitor Covid-19 severity?” attracted 64 responses that were nearly unanimous. Answers: Fibrin degradation products: 3 [5%] D-dimer: 53 [83%] PT and PTT: 3 [5%] Platelet count: 1 [2%] Other: 4 [6%] Several publications, especially from China, record the parallel use of FDPs and […]

Fibrinolysis

ISTH Guidelines for TTP

Here are the July, 2020 ISTH diagnostic guidelines for thrombotic thrombocytopenic purpura as reported at the recent digital congress: Zheng XL, Vesely SK, Cataland SR, et al. Guidelines for the diagnosis of thrombotic thrombocytopenic purpura. J Thromb Haemost 2020;pre-pub, doi: 10.1111/JTH.15006

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Thrombophilia

Thrombophilia

Intermountain States Seminar 10-18-20

October 2020 Quick Question: Inflammation

Covid-Coag Conversation Video

Covid-Coag Conversation 9-15-20: Reminder

August, 2020 Quick Question on D-dimer Results

Covid-Coag Conversation 9-15-20

Mixing Studies

Case: Consistent D-dimer Elevation

July, 2020 Quick Question on Covid Coag Results

ISTH Guidelines for TTP

George Fritsma MS MLS

Cheat Sheets from George

Questions or Comments?

Quick Question