Quick Question Archive

Quick Question: FVL Order

Our Quick Question for May, 2019 was “A rheumatologist orders a thrombophilia profile that includes a genotypic factor V Leiden mutation assay. You… A. Proceed with the FVL assay: 40% (14) B. First perform the phenotypic APCR: 51% (18) C. Cancel the order: 9% (3) George posted this because the American Society for Clinical Laboratory […]

Quick Question Archive

Quick Question: Pregnant Woman with DVT

Here is our April, 2019 Quick Question, Adapted from Walenga JM. Chapter 35–Normal Hemostasis. In Keohane EM, Otto CN, Walenga JM. Rodak’s Hematology, Clinical Principles and Applications, 6th Edition, 2020. ISBN 978-0-323-53045-3. A 33-year-old pregnant woman developed deep vein thrombosis in her left leg. She reported a family history—her mother had an episode of superficial […]

Quick Question Archive

Case: DVT During Pregnancy

Our Quick Question case study for April, 2019, is adapted from Chapter 35 of the March, 2019 6th edition of Rodak’s Hematology, Clinical Principles and Applications: A 33-year-old pregnant woman developed deep vein thrombosis in her left leg. She reported a family history–her mother had an episode of superficial thrombophlebitis and her brother had experienced […]

Lupus Anticoagulant

Specimen Integrity Survey Quick Question

Our March, 2019 Quick Question consists of a Survey Monkey survey (click or tap) on specimen integrity. Please see the entry for a full explanation.

Quick Question Archive

Quick Question: 41 YO Man With GI Bleeding Response

Our February, 2019 Quick Question was a case study entitled, “41-YO Man with GI Bleeding” (click or tap to review). For 56 responders, the answers and tallies were… Vitamin K deficiency 9% (5) Moderate liver disease 57% (32) Functional platelet disorder 4% (2) Disseminated intravascular coagulation 21% (12) Other: please provide a written response 9% […]

Bleeding Disorders

February Quick Question Reminder

Just a reminder, only two more days to answer our February 1 Quick Question. For our March Quick Question we will be turning to our Specimen Integrity Survey. Watch for your monthly Cheat Sheet early next week.

Quick Question Archive

Quick Question: 6 YO Boy with Chronic Bleeding

Please click or tap our December 31, 2018 Quick Question post, a case study of a 6-year-old boy with chronic bleeding. We had a 2018–19 record 76 responses. The choices and responses are as follows. Answers Platelet function abnormality: 10 (13%) Von Willebrand disease: 14 (18%) Factor VII deficiency: 4 (5%) Factor XII deficiency: 4 […]

Bleeding Disorders

Case: 6-year-old Boy with Chronic Bleeding

(Thanks to Dave McGlasson for this case study) A six-year-old boy presented with a history of joint bleeds, hematomas, and occasional deep muscular bleeds. His parents reported that he had experienced no umbilical bleeding but bled from circumcision at two days of age, reaching a hemoglobin level of 3.1 g/dL, requiring transfusions and surgery. There […]

Bleeding Disorders

Quick Question: Specimen Integrity Response

Our December, 2018 Quick Question on specimen integrity drew 46 responses. The question was, “How do you manage a plasma that appears to have fibrin strands?” Here are the answers: a. Reject and request a redraw: 41 (89%) b. Perform requested assay and report if non-critical: 1 (2%) c. Perform factor assays to confirm specimen […]

Quick Question Archive

Quick Question: Specimen Integrity

In follow-up to a December 1, 2018 post, Reference Lab Specimen Integrity, our December, 2018 Quick Question asks, “How do you manage a plasma that appears to have fibrin strands?” In case no answer matches your protocol, please provide a response below. Here is a response from Robyn Coleman: We would reject any sample for […]

Quick Question Archive

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George Fritsma is a medical laboratory scientist, educator, and author. George is a member of the International Society on Thrombosis and Hemostasis, the International Society for Laboratory Hematology, and the American Society for Clinical Laboratory Science.

Cheat Sheets from George

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