Quick Question Archive

April 2025 Quick Question: How to Measure Warfarin in a LAC Patient

Our April 2025 Quick Question is a poll that asks, “How do you measure warfarin in a patient with lupus anticoagulant (LAC)?” This question is a sequel to our March 2025 question, “How do you test for lupus anticoagulant?” that references the ISTH‘s most recent LAC guidelines, Devreese KMJ, Bertolaccini ML, Branch DW, et al. […]

Lupus Anticoagulant

March 2025 Quick Question: LAC Testing Outcome

Our March 2025 Quick Question asked, “How do you test for lupus anticoagulant?” The question drew 38 responses. DRVVT Screen/Confirm only: 4 (11%) PTT Screen/Confirm only: 2 (5%) First DRVVT S/C then PTT S/C if pos: 1 (3%) First PTT S/C then DRVVT S/C if pos: 3 (7%) Both DRVVT S/C & PTT S/C: 27 […]

Lupus Anticoagulant

March 2025 Quick Question: LAC Testing

The March 2025 QQ is now available to answer, it is a poll to learn how we perform lupus anticoagulant testing. If you have an alternative, please answer in the Comments section below.

February 2025 Quick Question: FXIII Deficiency

Our February 2025 QQ was a quiz that asked, “What factor deficiency is associated with poor wound healing?” The question attracted 60 participants who answered… FII: 4 (7%) FV: 5 (8%) FVIII: 9 (15%) FIX: 3 (4%) FXIII: 39 (65%) The large majority is correct. Here is the abstract from Luyendyk JP, Flick MJ, Wolberg AS. […]

Bleeding Disorders

February 2025 Quick Question

Our February 2025 Quick Question is a quiz that asks “What factor deficiency is associated with poor wound healing?” You may answer on the right and if convenient, add your comments below and watch for the results on or after March 1.

January 2025 Quick Question: PFA 100/200

Our January 2025 Quick Question asked: “To test for platelet function, how do you report PFA-100/200 collagen-epi (CEPI) and collagen-ADP (CADP) results?” Here are the responses from 35 participants: CEPI only, Neg/Pos: 1 (3%) CEPI only, CT seconds: 2 (6%) CEPI & CADP, Neg/Pos: 3 (9%) CEPI & CADP, CT: 23 (66%) We use the […]

Quick Question Archive

Dec 2024 QQ: Whole Blood Clot Detection

Our December 2024 Quick Question, “How do you detect small clots in whole blood specimens?” drew 44 responses. Here are our results… Plastic dowel: 0 Observe plasma: 1 (2%) Wooden dowel (stick): 34 (78%) Tilt tube and observe: 8 (18%) We don’t check for clots: 1 (2%, I–Geo–added this vote, it does not represent a […]

Quick Question Archive

November 2024 QQ: Cryoprecipitate

Our November 2024 Quick Question, which attracted 28 responses, asked, “Who invented cryoprecipitate?” Dr. E. J. Kohn: 1 (4%) Dr. Judith Pool: 19 (68%) Dr. Armand Quick: 3 (11%) Dr. Rudolph Virchow: 4 (13%) Dr. Kenneth Brinhous: 1 (4%) Comments: Cryoprecipitate (Cryo) was developed and produced by Judith Pool, PhD, 1919–1975, from Stanford University in […]

Quick Question Archive

Clot Detection in Whole Blood Specimens

I (Geo) received this message on 11-27-24 from Dr. Ludwig Albornoz: After a simple search on Google, we landed on your website, regarding a practice of detecting and removing fibrin and or blood clots in clinical laboratory blood specimens by using a mechanical method, either plastic or wooden rods, which I introduced for use in […]

Specimen Management

November 2024 Quick Question: History

Our November Quick Question, seen on the right, is a simple quiz with one correct answer. Please comment on your response or add your favorite historical anecdotes.

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George Fritsma is a medical laboratory scientist, educator, and author. George holds faculty appointments with Rutgers University and Michigan State University, and is a member of the International Society on Thrombosis and Hemostasis, American Association of Clinical Chemists, and American Society for Clinical Laboratory Science.

Cheat Sheets from George

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