Primary CVD Disease: Is Low Dose ASA Effective?

Thanks to Dean Willett, Precision BioLogic Inc, for pointing me to this October 12, 2021 US Preventive Services Task Force release, “Aspirin Use to Prevent Cardiovascular Disease: Preventive Medication,” which recommends against daily low-dose aspirin as a means to reduce the risk of cardiovascular disease, ischemic stroke, and colorectal cancer regardless of age or comorbities. […]

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Antiplatelet Therapy

Jun 25 2021

george

New Fundamentals in Hemostasis

Thanks to my colleague Carlo Ledesma, MS, SH(ASCP)QLS, MT(ASCPi), MT(AMT) for pointing me to an in-depth hemostasis review, Versteeg HH, Heemskerk JWM, Levi M, Reitsma PH. New Fundamentals in Hemostasis. Physiol Rev 2013;93:327–58. This is a valuable teaching resource that helps elucidate the cell-based hemostasis model.

Arterial Thrombosis

Covid-Coag Conversation 9-15-20

You are invited to our Tuesday, September 15, 2020 webinar, Covid-Associated Coagulopathy: A Conversation about the Controversies and Confusion featuring pathology expert Andrew J. Goodwin, MD, University of Vermont Medical Center Laboratory Director. Click https://conta.cc/3aMDoNp for the eblast or bit.ly/COVID-Coag to go directly to the registration page. Covid-Coag is a PACE-accredited one-hour presentation, 5–6 PM […]

Arterial Thrombosis

Covid and Hemostasis Riley Article

For a succinct summary of hemostasis mechanisms and management in the Covid-19 infection, see Riley P. Pandemic care: The need for hemostasis testing in critically ill COVID-19 patients. MLO 5-20-20, accessed 7-7-20. Also visit Stago’s Edvantage Virtual University for their recent program, Thromboembolism in COVID-19: Laboratory Considerations by Michael P Gulseth, Pharm. D., BCPS, FMSHP, […]

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Anticoagulant Therapy

Jul 1 2020

george

July, 2020 Quick Question: Covid

Our July 2020 Quick Question highlights the hemostasis laboratory’s responsibility in monitoring the thrombotic aspects of Covid disease progression and recovery. Please provide your answer to “What assay does your lab use to monitor Covid-19 severity?” Feel free to add comments about this critical need using the Comments link or by emailing George at [email protected].

Arterial Thrombosis

More on Covid and LAC

Thanks to Dr. Ali Sadeghi-Khomami, Precision BioLogic Inc., for sending a current editorial in press, Aubignat M, Godefroy O. COVID-19 and ischemic stroke: Should we systematically look for lupus anticoagulant and antiphospholipid antibodies? Revue neurologique 2020, https://doi.org/10.1016/j.neurol.2020.05.001. Please refer to our May 6 entry on antiphospholipid syndrome and the comment from Dr. Ning Tang. The […]

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Anticoagulant Therapy

Jun 29 2019

george

Quick Question: TTP Laboratory Assay

Our June, 2019 Quick Question generated a near-unanimous response from 68 voters: What laboratory assay confirms thrombotic thrombocytopenic purpura (TTP)? Shiga toxin test: 3% (2) Complement C3 level: 7% (5) ADAMTS13 activity: 83% (56) VWF multimers: 7% (5) The Shiga toxin test correlates to Shiga toxin-induced hemolytic-uremic syndrome (ST-HUS), the “classic” HUS detected mainly in […]

Arterial Thrombosis

Wearable Clot Detector

Nephrologist Vinay Narasimha Krishna, M.D, University of Alabama at Birmingham, developed a wearable clot detection device for which he received one of 15 KidneyX Redesign Dialysis prizes from the U.S. Department of Health and Human Services and the American Society of Nephrology. The device is designed to be worn over the dialysis fistula in real […]

Arterial Thrombosis

Hyperglycemia and Stroke Outcome

The iSPOT study links treatment outcomes for acute isechemic stroke in hyperglycemic patients with markers of tissue factor pathway activation, as reported on March 5, 2019 in The Heart.org. Click or tap here for details.

Arterial Thrombosis

REDUCE-IT Trial Results

Today, Saturday, November 10, 2018, Dr. Deepak Bhatt, principal investigator of the Evaluation of the Effect of AMR101 on Cardiovascular Health and Mortality in Hypertriglyceridemic Patients With Cardiovascular Disease or at High Risk for Cardiovascular Disease: REDUCE-IT (Reduction of Cardiovascular Events With EPA – Intervention Trial) reported on encouraging results of the use of high-dose […]

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Antiplatelet Therapy

Arterial Thrombosis

Primary CVD Disease: Is Low Dose ASA Effective?

New Fundamentals in Hemostasis

Covid-Coag Conversation 9-15-20

Covid and Hemostasis Riley Article

July, 2020 Quick Question: Covid

More on Covid and LAC

Quick Question: TTP Laboratory Assay

Wearable Clot Detector

Hyperglycemia and Stroke Outcome

REDUCE-IT Trial Results

George Fritsma MS MLS

Cheat Sheets from George

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Quick Question