REDUCE-IT Trial Results

Today, Saturday, November 10, 2018, Dr. Deepak Bhatt, principal investigator of the Evaluation of the Effect of AMR101 on Cardiovascular Health and Mortality in Hypertriglyceridemic Patients With Cardiovascular Disease or at High Risk for Cardiovascular Disease: REDUCE-IT (Reduction of Cardiovascular Events With EPA – Intervention Trial) reported on encouraging results of the use of high-dose […]

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Antiplatelet Therapy

Nov 10 2018

george

VITAL Trial Results

Click or tap here to learn the results of the VITAL trial conducted by Joann Manson, MD DPH, Beth Israel. The trial looked at the primary endpoints of major cardiovascular disease events and invasive cancer in subjects taking marine omega-3 fatty acids (Omacor® fish oil, (eicosapentaenoic acid [EPA] and docosahexaenoic acid [DHA]], 1 g daily, […]

Antiplatelet Therapy

Research Fellowship Applications Now Open

Dear George: We are pleased to announce that applications are now open for the 2019 NASTH Sponsored Research Fellowships, an 8 – 10 week program for medical, PhD, MD/PhD, or PharmD students working on targeted research projects in hemostasis and thrombosis. Proposed projects may be lab-based, clinical or epidemiologic in design. The program includes a […]

Events

CoaguCheck Test Strip Recall

Thanks to Ali Sadeghi-Khomami PhD, Precision BioLogic, and Joan Polancic, MS MLS, Denver Health, for the heads-up on this announcemment: Roche Diagnostics, the manufacturer of CoaguChek meters and test strips, is recalling the CoaguChek XS PT Test Strips due to inaccurate INR test results, when compared to laboratory results. Roche re-calibrated the CoaguChek XS PT […]

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Anticoagulant Therapy

Oct 30 2018

george

Aspirin Efficacy

Here is a reference to a brilliant review of current aspirin efficacy studies, focusing especially on the prospective random control trial ASPREE published in the September, 2018 New England Journal of Medicine. Lippi G, Danese E, Favaloro EL. Harms and Benefits of Using Aspirin for Primary Prevention of Cardiovascular Disease: A Narrative Overview. Semin Hemostas […]

Arterial Thrombosis

Quick Question: Normalizing DRVVT Ratio Results

For our October, 2018 Quick Question we asked, “For lupus anticoagulant testing, how do you express the DRVVT screen and confirm results?” Here are the answers from 36 respondents: a. Ratio of screen to confirm: 17 = 47% b. Ratio of screen to confirm normalized to MRI: 17 = 47% c. Difference of screen and […]

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Quick Question Archive

Oct 26 2018

george

When to Label Tubes: Reprise

On January 1, 2018, I posted the outcomes of our December, 2017 Quick Question, “When is the correct time to label blood specimen tubes?” Subsequent to this posting, Dennis Ernst, Dave McGlasson, and I co-authored an editorial, “Labeling tubes before collection threatens patient safety,” in the February, 2018 issue of Annals of Blood. Below are […]

Specimen Management

Case: elevated D-dimer

Here is a case presented by a participant. This was posted as a comment to an October 21, 2011 string, D-dimer Lot-to-Lot QC and reproduced here. “I have been getting dizzy when I stand up and my calves burn and cramp. When I bend over I get short of breath to the point that it […]

Posts

Aspirin for TKR?

Thanks to Dave McGlasson for sending Aspirin, Anticoagulants Similarly Prevent VTE After TKA from MPR Publications. I’ve lately been hearing anecdotes of patients being prescribed aspirin after total hip or knee replacement, and I know of one person, a hemostasis expert, who was prescribed no antithrombotic therapy subsequent to TKRs on both knees with no […]

Antiplatelet Therapy

Hemophilia B and Extended Half-life Concentrates

Here is another note from Paul Riley, PhD examining the effects of extended half-life factor IX concentrates. on hemophilia B testing. Hemophilia B1: Therapy Classes and Monitoring Factor IX Inhibitor? Y/N Y/N Prophylaxis Conventional half-life recombinant or plasma-derived FIX Extended half-life FIX Preferred assay to measure FIX activity OSA2 (or CSA) CSA (or OSA) 1. […]

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Bleeding Disorders

All Posts

REDUCE-IT Trial Results

VITAL Trial Results

Research Fellowship Applications Now Open

CoaguCheck Test Strip Recall

Aspirin Efficacy

Quick Question: Normalizing DRVVT Ratio Results

When to Label Tubes: Reprise

Case: elevated D-dimer

Aspirin for TKR?

Hemophilia B and Extended Half-life Concentrates

George Fritsma MS MLS

Cheat Sheets from George

Questions or Comments?

Quick Question