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Are we Overusing LMWH?

A provocative open-access article posted on LinkedIn by Dr. Emmanuel Favaloro suggesting we are overusing LMWH: Gurumurthy G, Fan B, Gurumurthy J, et al. Should we focus on sustainable thromboprophylaxis and avoid overuse of low-molecular-weight heparins? Research and Practice in Thrombosis and Haemostasis, 2026; 10. DOI: 10.1016/j.rpth.2026.106794. Abstract Low-molecular-weight heparins (LMWHs) have become a near-routine prescription […]

Anticoagulant Therapy

Why Clotting Patients Bleed

Abdul Mannan, Consultant Haematologist at Betsi Cadwaladr University Health Board, shared a column, Why Clotting Patients Bleed, in Hemostasis Today.

DOAC Monitoring–What to Order

Ifeanyichukwu Ifechidere, Specialist Biomedical Scientist at Sheffield Teaching Hospital NHS Foundation Trust, shared her column, DOAC Monitoring–What to Order, When, and Why in Hemostasis Today.

Anticoagulant Therapy

July 2026 Cheat Sheet

Click the Cheat Sheet for your July 2026 edition. You can also request your personal Cheat Sheet with links to recent Fritsma Factor entries by completing the “Sign Up” entry on the right. Fritsma Factor, Educational Modules, and Resources are provided compliments of Precision BioLogic Inc.

July 2026 QQ: VWD Therapeutic

We commemorate the 1926 publication by Finnish physician, Eric von Willebrand, Von Willebrand, E A (1926). “Hereditär pseudohemofili”. Finska Läkaresällskapets Handlingar (in Swedish). 68: 87–112. Dr. von Willebrand’s title, “Hereditary Pseudohemophilia,” was updated to our current name, von Willebrand disease, in the late 1930s, and the responsible protein was named von Willebrand factor in 1971. […]

Bleeding Disorders

June 2026 QQ Review: VWF Gain of Function

Our June 2026 QQ, which drew 30 responses, asked, “What VWD subtype is caused by a VWF gain of function?” Here are your responses: VWD type 1: 3 (10%) VWD subtype 2A: 1 (3%) VWD subtype 2B: 24 (80%) VWD subtype 2M: 2 (7%) VWD subtype 2N: 0 VWD type 1 is the quantitative form […]

Bleeding Disorders

A New Era in VWD Treatment

Click here for an informative LinkedIn/Hemostasis Today post from Shadi Tabibian, Deputy of Research at Blood Diseases Research Centers in Iran University of Medical Sciences, A New Era in VWD Treatment. For decades, the management of VWD has relied mainly on VWF concentrates, desmopressin, antifibrinolytic agents, and hormonal therapies. Although these treatments remain effective for […]

Bleeding Disorders

Review: Diagnosis and Management of Hemophilia A & B

Click here for an open-access review: Lim MY, Ardila J, Castaman G, et al. Diagnosis and management of hemophilia A and B. J Thromb Haemost. 2026;24:2341–54. doi: 10.1016/j.jtha.2026.04.005. PMID: 41967712. Abstract Hemophilia A and hemophilia B are inherited bleeding disorders caused by a deficiency or absence of coagulation factor FVIII and FIX, respectively. The severity […]

Bleeding Disorders

What is CAPS?

Here is an illustrated Hemostasis Today description by Dr. Abdul Mannan, Consultant Haematologist at Betsi Cadwaladr University Health Board, of catastrophic antiphospholipid syndrome (CAPS), which accounts for 1% of antiphospholipid syndrome (APS) diagnoses. As Dr. Mannan reports, the APL assay is a vital diagnostic consideration of this acute condition.

Lupus Anticoagulant

Coag Conversation: 100 Years of Von Willebrand Disease and Upcoming Advances

Click here for the first of our three-part Coag Conversation series, 100 Years of von Willebrand disease. featuring George Fritsma interviewing Robert Sidonio, MD. Dr. Sidonio is the Medical Director of the Clinical Research Office at the Aflac Cancer and Blood Disorders Center of Children’s Healthcare of Atlanta and is the Professor of Pediatrics, Emory […]

Bleeding Disorders

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George Fritsma is a medical laboratory scientist, educator, and author. George is a member of the International Society on Thrombosis and Hemostasis, the International Society for Laboratory Hematology, and the American Society for Clinical Laboratory Science.

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