World Thrombosis Day 10-13-21

In case you missed it, click here for a review of yesterday’s World Thrombosis Day [WTD] activities and materials. “Venous thromboembolism [VTE] is a condition in which a blood clot forms, most often in the deep veins of the leg, groin or arm [deep vein thrombosis, DVT] and travels in the circulation, lodging in the […]

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Thrombophilia

Oct 3 2021

george

IMSS Handouts 10-3-21

George has attached updated handouts for our Intermountain States Seminar 10-3-21 presentations. Click below to download. Looking forward to the day! TTP and the TMAs in One-per-Page Format TTP and the TMAs in Six-per-Page Format Hematology Specimen Management in One-per-Page Format Hematology Specimen Management in Six-per-Page Format

Events

September 2021 Quick Question: TEG

Our September 2021 Quick Question attracted only 14 responses, perhaps reflecting the minimal communication between the central laboratory and the anesthesiology service in most operating rooms. Our question was “What is the favorite near-patient viscoelastic test of US anesthesiologists?” Here are your answers: Rotational thromboelastometry [ROTEM]: 14% [2] Resonance sonorheometry [Quantra]: 7% [1] Activated clotting […]

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Global Hemostasis Assays

Sep 23 2021

george

Blood Collection Tube Shortages

In a follow-up to our June 2021 posts describing blue-closure [3.2% sodium citrate] tube shortage, it appears from several anecdotes that while the industry is slowly catching up to blue-closure tube demands, there remain shortages in green-closure [heparin] and other tubes. Meanwhile, we alert worldwide facilities to the availability of tubes through online suppliers of […]

Specimen Management

McMaster Update in Thromboembolism

The McMaster University Continuing Professional Development Office is pleased to present the virtual Seventeenth Annual McMaster Update in Thromboembolism, Friday, October 1, 2021. Thank you to Elaine Benoit, Precision BioLogic, for the heads-up.

Thrombophilia

Coag Specimens, Delayed Analysis, Centrifugation

From a colleague: Hi George, I was having a discussion with a colleague regarding the proper or best way to handle a coagulation sample if the processing was going to be delayed [~4 hrs]. Your name popped up, so hence my email: Option 1: the sample is spun when received and then analyzed later. Our […]

Specimen Management

August, 2021 Quick Question: Factor Deficiency

Our August 2021 Quick Question, which asks, “Which factor deficiency causes the smallest risk of bleeding?” drew a respectable 48 votes. Answers: VWF deficiency: 9% [4] Factor X deficiency: 4% [2] Factor XI deficiency: 7% [3] Factor XII deficiency: 52% [24] Prekallikrein deficiency: 28% [13] Both 4 and 5 are correct, deficiencies of contact factors […]

Bleeding Disorders

Webinar: Rare Thrombotic Response to a SARS-CoV-2 Vaccine

Please join us for a compelling discussion about the rare, unusual thrombotic events that develop in association with thrombocytopenia approximately one to two weeks after vaccination with a SARS-CoV-2 vaccine. This incidence of thrombocytopenia is mediated by platelet-activating antibodies against platelet-factor 4, without any exposure to heparin, and it mimics heparin-induced thrombocytopenia. Don’t miss this […]

Events

Factor V Inhibitor

I [Geo] am preparing an audio PowerPoint module describing the primary coagulation assays, PT, PTT, TT, and fibrinogen [Fg] assays. I asked several colleagues if we continue to encounter factor V inhibitors. Before ~2010 we encountered anti-FV and sometimes anti-FV plus anti-FII [prothrombin] as cross-reacting antibodies that arose in response to bovine thrombin used in […]

Screening Assays

Chromogenic Vs. Clot-based FVIII Assays

The Precision BioLogic Inc. and the Affinity Biologicals, Inc. research team presented a poster comparing chromogenic versus clot-based factor VIII assays measuring pegylated factor VIII therapeutic concentrate at the July 17–21, 2021 meeting of the International Society on Thrombosis and Haemostasis. The poster is now available for your download: Tara Quinton, John Fraser, Karen M. […]

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Bleeding Disorders

All Posts

World Thrombosis Day 10-13-21

IMSS Handouts 10-3-21

September 2021 Quick Question: TEG

Blood Collection Tube Shortages

McMaster Update in Thromboembolism

Coag Specimens, Delayed Analysis, Centrifugation

August, 2021 Quick Question: Factor Deficiency

Webinar: Rare Thrombotic Response to a SARS-CoV-2 Vaccine

Factor V Inhibitor

Chromogenic Vs. Clot-based FVIII Assays

George Fritsma MS MLS

Cheat Sheets from George

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Quick Question