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Oct 10 2026
george

Illustrated Review: Acquired Hemophilia A

Here is a richly illustrated review of acquired hemophilia A: Guillet B, d’Oiron R, Lacroix-Desmazes S, et al. Acquired hemophilia A: an illustrated review based on the French National Guidelines. Res Pract Thromb Haemost. 2026;10(5):106820. doi: 10.1016/j.rpth.2026.106820. PMID: 42657325; PMCID: PMC13508639. Abstract Acquired hemophilia A is a rare but potentially life-threatening autoimmune bleeding disorder caused […]
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Bleeding Disorders
Oct 10 2026
george

Transfusion Journal Case Series: Inherited FX Deficiency

Here is an open-access review of inherited FX disorders: Chitlur M, Amos LE, Reding MT, Sabo C, Acharya SS. Characterization and management of patients with hereditary factor X deficiency: A case series. Transfusion. 2025;65(10):1786-1792. doi: 10.1111/trf.18377. PMID: 41104456; PMCID: PMC12531909. Abstract Background: Hereditary factor X deficiency (HFXD) is an ultra-rare, autosomal recessive bleeding disorder that […]
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Bleeding Disorders
Oct 10 2026
george

Review: Inherited Bleeding Disorder in Women

Select this open-access review of inherited bleeding disorders in women: Connell NT, Davies J, Abdul-Kadir R, Kaplan Z. Obstetric and gynaecologic considerations in inherited bleeding disorders. Haemophilia. 2026. doi: 10.1111/hae.70267. PMID: 41988968. Abstract Women and girls with inherited bleeding disorders (IBD) face distinct gynaecologic and obstetric challenges, largely due to increased bleeding risk during key […]
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Bleeding Disorders
Oct 9 2026
george

STH Review: Hemostasis and Menstrual Bleeding

This year’s World Thrombosis Day focuses on hemostasis issues in women. Select this open-access Seminars review: Dodart R, Ku DN. What stops menstrual bleeding? Hemostatic mechanisms in the menstruating endometrium. Semin Thromb Hemost. 2026. doi: 10.1055/a-2967-9335. PMID: 42843808. Abstract Menstrual bleeding is one of the most common physiological bleeding events in humans, yet the mechanisms […]
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Bleeding Disorders
Oct 9 2026
george

Prospective Analysis: The Relationship of D-dimer and Heart Failure

Check with your medical library for He X, Zheng R, Zheng R. The relationship between D-dimer and the risk for adverse outcomes in patients with heart failure. Lab Med. 2026: lmag072. doi: 10.1093/labmed/lmag072. PMID: 42832500. Abstract Introduction Insufficient evidence exists for the association between serum dimerized plasmin fragment D (D-dimer), a biomarker for screening thromboembolic […]
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Fibrinolysis
Oct 1 2026
george

July 2026 CAP Today Q & A Column: Lipoprotein (a).

Q. Our providers pointed out that lipoprotein(a) results from different laboratories are discordant, so they asked us to bring the assay in-house. Is this a good idea? A. Lipoprotein(a), or Lp(a), is a prothrombotic, proinflammatory, and atherogenic cholesterol-rich particle. Plasma concentration of Lp(a) is an important genetic determinant of atherosclerotic cardiovascular disease (ASCVD) risk, and […]
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Thrombophilia
Oct 1 2026
george

October 2026 QQ: Which is NOT an APL?

Our October 2026 Quick Question is a quiz that asks, “Which is NOT an antiphospholipid antibody?” The choices are…  Anti beta-2 glycoprotein 1  Alpha-2 antiplasmin  Lupus anticoagulant  Antiprothrombin  Anticardiolipin Antiphospholipid antibodies are acquired autoantibodies that bind phospholipid-bound proteins. Please go to the question on the right of your screen, make your selection, and add your […]
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George Fritsma MS MLS

George Fritsma is a medical laboratory scientist, educator, and author. George  is a member of the International Society on Thrombosis and Hemostasis, the International Society for Laboratory Hematology, and the American Society for Clinical Laboratory Science.

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Quick Question

Which is an antifibrinolytic used to control bleeding?