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Aug 26 2026
george

Circadian Clock Regulates Hemostasis

This 2026 advanced open-access meta-analysis examines the effects of the circadian clock, accounting for the prevalence of morning strokes and AMIs. Ibrahim Z, Murphy RP, Guillaume GC, Arya R, Goswami N. Circadian clock regulation of hemostasis: a systematic review of molecular pathways. Res Pract Thromb Haemost. 2026 May 8;10(4):106642. doi: 10.1016/j.rpth.2026.106642. PMID: 42293739; PMCID: PMC13264353. […]
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Arterial Thrombosis
Aug 26 2026
george

Specimen Volume Management Minimizes Blood Loss

This open-access editorial addresses an essential concern in hemostasis and all areas of laboratory medicine. Šimundić AM, Jovičić S, Cornes M, et al. Sample volume management: the role of the clinical laboratory in minimizing diagnostic blood loss. Clin Chem Lab Med. 2026 Aug 24. doi: 10.1515/cclm-2026-1125. Epub ahead of print. PMID: 42631442. Abstract Hospital-acquired anemia […]
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Specimen Management
Aug 24 2026
george

DOAC Pharmacodynamics and Potential Near-patient Decision Making

Access your ISTH membership or medical library for a ground-breaking JTH Forum article: Shaw JR, Ansell J. A light in the dark-reframing direct oral anticoagulant pharmacokinetics and pharmacodynamics for near-patient decision-making. J Thromb Haemost. 2026;24(8):2726-2731. doi: 10.1016/j.jtha.2026.05.016. Epub 2026 May 21. PMID: 42173287. Abstract Direct oral anticoagulant (DOAC) level testing is needed most when decisions […]
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Anticoagulant Therapy
Aug 22 2026
george

Pre-barcoded Tubes Reduce Misidentification Rates

Here is an open-access survey report: Jovičić S, Verdonck A, Lippi G, Ruven H, Šimundić AM. How do pre-barcoded tubes improve preanalytical workflow? A survey study. Clin Chem Lab Med. 2026 Aug 21. doi: 10.1515/cclm-2026-0836. PMID: 42617137. Abstract Objectives Preanalytical errors account for approximately 60–70 % of all laboratory errors, with sample misidentification among the most […]
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Specimen Management
Aug 18 2026
george

Hemophilia A Patient Satisfaction With Extended Half-life Altuviiio® Therapy

Click here for an open-access post hoc study report on patient satisfaction with once-weekly Altuviiio® (Efanesoctocog alfa) therapy: Spasov E, Quon D, Fukutake K, et al. Treatment satisfaction and patient preference for efanesoctocog alfa over previous hemophilia A treatment: Results from the XTEND-1 phase 3 clinical trial. Curr Ther Res Clin Exp. 2026;105:100839. doi: 10.1016/j.curtheres.2026.100839. […]
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Bleeding Disorders
Aug 17 2026
george

Simplified DOAC–Stop Proof of Concept

Click here for this 2024 open-access article describing the use of DOAC-Stop®: Exner T, Dangol M, Favaloro EJ. Simplified method for removing direct oral anticoagulant interference in mechanical coagulation test systems–a proof of concept. J Clin Med. 2024;13:1042. doi: 10.3390/jcm13041042. PMID: 38398355; PMCID: PMC10889288. Abstract Background: Direct oral anticoagulants (DOACs) cause unwanted interference in various […]
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Anticoagulant Therapy
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George Fritsma MS MLS

George Fritsma is a medical laboratory scientist, educator, and author. George  is a member of the International Society on Thrombosis and Hemostasis, the International Society for Laboratory Hematology, and the American Society for Clinical Laboratory Science.

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In your facility, what AC is used for LAC patients with VTE?