POCT ACT and Anti-Xa for ECMO

From Deanna Miller, Point of Care Testing (POCT) Coordinator at Children’s of Alabama: We have recently merged our extracorporeal membrane oxidation (ECMO) team with the cardiovascular team from the University of Alabama at Birmingham (UAB) and we are doing all pediatric cardiovascular cases at Children’s now. We would like some insight into monitoring coagulation using the activated coagulation time […]

Comments (2)

Anticoagulant Therapy

May 8 2013

george

TEG in a Community Hospital

From Annette Gaskill, Estes Park Medical Center: I’m a MT at a small critical care hospital and also am part of our facility’s trauma committee. In our discussions of trauma cases involving patients already anticoagulated, our surgeon has asked me about thromboelastograms. Our coagulation menu is PT, PTT, and D-dimer; anything else is sent out. We only […]

Bleeding Disorders

Anticoagulant Reversal Protocols

From Scott Cornelius at Johnson & Johnson, I am interested in finding out if you have any samples of what good bleeding protocols for large teaching hospitals are like. With all of the new oral agents on the market there surely are many new challenges in managing patients with ICH and other serious bleeding complications. Thanks for your […]

Comments (1)

Anticoagulant Therapy

May 2 2013

george

Post-partum Hemorrhage and Component Therapy

Originally posted on October 11, 2011. Hi George! As always, I enjoy this educational resource very much! My question is: Why do healthy women who experience post-partum hemorrhage (PPH) seem to “autocorrect” their coagulopathy with very little help from component therapy? I have noted that once the bleeding site has been tended to, the patient […]

Bleeding Disorders

Overfilled Tubes

Here is a question originally posted November 4, 2011 that did not attract discussion at the time: I received a note from David Chance, Good Samaritan Medical Center, Corvallis OR, commenting that, unlike underfilled coagulation specimen (blue-closure) tubes; overfilling tubes, unless clots are present, does not affect coagulation results. Overfilling may occur when a specimen is […]

Specimen Management

INR Reference Range?

A message from Patti Richardson and Dr. Manjula Balasubramanian, St Christopher’s Hospital for Children, Philadelphia, PA (originally posted November, 2011): Is it necessary to have a reference range for the international normalized ratio (INR)? It is a calculated value. If so, should these be derived from the normal prothrombin time (PT) ranges? The Heme CAP checklist does not […]

Comments (0)

Anticoagulant Therapy

Apr 30 2013

george

Specimen Freezing and FVII Activation

Oiginally posted on October 25, 2011. From Kim Kinney at Indiana University (formerly Clarian) Health Center: Hi George, Even though I am not in coag much any more I still get a ton of questions. One of our TC’s was questioning our storage of PT/INR specimens. We follow the current recommendations of room temperature for 24 hours. […]

Specimen Management

Assaying for HMWK and PK

From Michele L. Drejka, Lead Technologist, Barnabas Health, Newark, NJ: Hi George, Sorry to be redundant, but I posted this in ‘Comments,’ however I actually need an answer to my question below, so I am repeating here: Regarding prolonged activation times-I’m getting frustrated. I had more success with playing with this 15 years ago! However, this is […]

Coagulation Factors

Platelet Count in APA

From Kathleen Doig, PhD, Professor, Biomedical Laboratory Diagnostics at Michigan State University. George – a question arose in our senior Medical Laboratory Science class today as students were constructing algorithms to investigate some case problems I gave them. Here’s the question: What is the platelet count for patients with thrombosis due to antiphospholipid syndrome (APA)? George […]

Thrombophilia

Douglas Triplett, MD

Frank Toffoloni, Precision BioLogic Inc, called yesterday with the news that Dr. Douglas Triplett of Muncie, Indiana, passed away on Saturday, April 20, 2013, following an extended illness. Dr. Triplett was a mentor to all who specialize in hemostasis and a primary influence on diagnostic approaches to bleeding and clotting disorders. We still keep his 1982 textbook, Laboratory Evaluation […]

Comments (1)

Events

All Posts

POCT ACT and Anti-Xa for ECMO

TEG in a Community Hospital

Anticoagulant Reversal Protocols

Post-partum Hemorrhage and Component Therapy

Overfilled Tubes

INR Reference Range?

Specimen Freezing and FVII Activation

Assaying for HMWK and PK

Platelet Count in APA

Douglas Triplett, MD

George Fritsma MS MLS

Cheat Sheets from George

Questions or Comments?

Quick Question