More on Whole Blood Aggs

Here’s additional follow-up to Heather DeVries’s February 9 whole blood lumiaggregometry discussion, which attracted comments from Bob Gosselin, Dave McGlasson, and Drs. Catherine Hayward and Emmanuel Favaloro. Dr. Favaloro references the effort to clean cuvettes and probes in the whole blood system, so I want to reassure Heather that these components are now disposable. I’m […]

Comments (1)

Platelet Function Testing

Feb 9 2017

george

More on Polycythemia and Anticoagulant Volume

More on anticoagulant adjustment from Heather DeVries: There is more to our story on adjusting sodium citrate for high hematocrits. We have a pediatric patient who is getting multiple draws, for multiple assays, throughout the day. Sometimes there is PT and/or PTT, but sometimes not. The techs are confused as to when the draw must […]

Specimen Management

Whole Blood Lumiaggregometry

From Heather DeVries, Indiana University Health: We currently perform our platelet aggregations using PRP, but would like to investigate whole blood aggregometry. Our pathologist feels that if we do that, we should also look into lumiaggregometry. He does agree that it would improve our sensitivity to platelet functions disorders (i.e. storage pool disease), but wanted […]

Comments (3)

Platelet Function Testing

Feb 9 2017

george

Polycythemia and Anticoagulant Volume

From Heather DeVries, Indiana University Health: Greetings George! A couple of sites within our system are evaluating our process for correcting tubes. One mentioned CLSI guidelines, and when I looked, they keep it very simple, saying that removal of 0.1 mL of citrate will cover hematocrits between 55 and 65%. Historically, we have calculated to […]

Specimen Management

Off Label Low Dose DOACs

Click or tap here for Dr. Samual Goldhaber’s video clip describing the prevalence of off-label low dosing of dabigatran, rivaroxaban, and apixaban.

Comments (0)

Anticoagulant Therapy

Jan 24 2017

george

Diluting Chromogenic Anti-Xa’s For Heparin

From Denise Jones: Good afternoon George, A colleague of mine recently questioned why we were diluting our anti-Xa heparins and anti-Xa LMWHs. We do not dilute Arixtra or rivaroxaban. What is standard practice for other labs? We use Stago Liquid Anti-Xa reagent and a hybrid curve. Thank you. Hi, Denise, the specimen dilutions for chromogenic […]

Comments (0)

Anticoagulant Therapy

Jan 20 2017

george

IL Acquires Accriva

Today, January 20, 2017, Werfen (Barcelona) and their partner, Instrumentation Laboratory (IL, New Bedford, MA), announced their acquisition of Accriva Diagnostics of San Diego. Accriva manufactures and distributes the Hemochron coagulation testing instrument, which performs point of care PT/INR, PTT, and ACT assays, and the VerifyNow antiplatelet therapeutic efficacy device. Click or tap here for […]

Events

2017 NASTH Fellowship

Second notice, forwarded on behalf of the North American Society on Thrombosis and Hemostasis: Dear NASTH Members, The deadline for Mentor Requests for the 2017 Fellowships is extended to February 10. We are in the midst of our application period for the 2017 NASTH Sponsored Research Fellowships, an 8 – 10 week program for […]

Events

Apixaban After TAVR in AF

A January, 2017 publication indicates that apixaban (Eliquis) yields fewer bleeds, less kidney damage, and fewer strokes in patients with atrial fibrillation after transfemoral aortic valve replacement (TAVR) over the first 30 days of treatment. See Seeger J, Gonska B, Rodewald C, Rottbauer W, Wöhrle J. Apixaban in patients with atrial fibrillation after transfemoral aortic valve replacement (TAVR). JACC: Cardiovascular Interventions 2017;10: DOI: […]

Comments (0)

Anticoagulant Therapy

Jan 12 2017

george

What is SEER Sonorheometry?

A colleague saw our January 10, 2017 entry describing T2MR, an emerging global hemostasis methodology, and responded with information about sonic estimation of elasticity via resonance (SEER) sonorheometry, a non-contact technology that employs ultrasound to measure whole blood parameters similar to the viscoelasticity data generated in thromboelastography (TEG) and thromboelastometry (TEM). The technology measures acoustic […]

Comments (0)

Global Hemostasis Assays

All Posts

More on Whole Blood Aggs

More on Polycythemia and Anticoagulant Volume

Whole Blood Lumiaggregometry

Polycythemia and Anticoagulant Volume

Off Label Low Dose DOACs

Diluting Chromogenic Anti-Xa’s For Heparin

IL Acquires Accriva

2017 NASTH Fellowship

Apixaban After TAVR in AF

What is SEER Sonorheometry?

George Fritsma MS MLS

Cheat Sheets from George

Questions or Comments?

Quick Question