May We Load Syringes with Anticoagulant?

Though we collect most hemostasis specimens using evacuated tubes, we often resort to syringes when patient veins are small or fragile. Many of us specify syringe collection for global whole blood assays and platelet function tests. George recalls a time when we would load the syringe with a measured volume of sodium citrate anticoagulant prior […]

Comments (1)

Specimen Management

Jul 8 2017

george

THSNA Award

The Thrombosis and Hemostasis Societies of North America announce their THSNA Travel to a Mentor Award, deadline September 1, 2017. Please tap or click here for the details.

Events

Webinar: Hemostasis and Women’s Health

Thanks to Dr. Paul Riley of Stago for his announcement of Stago’s Monday, August 7 Webinar on Hemostasis and Women’s Health. Click or tap here to register.

Events

Mixing Studies: 4:1?

From Dr. Deanna Franke, Carolinas HealthCare System: Thank you so much for all the valuable resource information on your website! My question relates to use of variations of mixing studies–specifically the use of dilutions during mixing studies: 1:1 vs 4:1 and saline mix. In what situations is it appropriate to use these variations? Hello, Dr. […]

Mixing Studies

Quick Question: Specimen Storage

On June 28, hemostasis researcher Dave McGlasson asked George, “what temperatures do most of us use to store centrifuged, platelet-poor plasma when testing is delayed?” We assumed most of us use –70ºC freezers, but it may be that many lab practitioners use alternative specimen storage protocols. George offered to post Dave’s question as our July, […]

Specimen Management

Quick Question: Mixing Study Results

The stem of our June, 2017 Quick Question was, “In a PTT mixing study, the patient’s initial PTT is 67 s, RI 25–35. The PTT is repeated after mixing 1:1 with NP, and the new result is 63 s, NP 30 s. What do you do next?” This was a quiz question with a correct […]

Mixing Studies

Nijmegen Bethesda Assay

Dr. Ali Sadeghi-Khomami, Precision BioLogic Inc., provided these in-depth technical questions about the Nijmegen Bethesda Assay (NBA), which we use to quantitate specific factor inhibitors such as anti-factor VIII or anti-factor IX. George forwarded his questions to Connie Miller and Amanda Payne, US Centers for Disease Control and Prevention (CDC) who have been working on […]

Bleeding Disorders

Hemorrhage Management

George recommends the June, 2017 CAP Today article, Life-threatening Bleeding–What’s the Right Call? The article features Drs. Theresa Nester and Tom DeLoughery and provides practical advice for massive blood loss and transfusion protocols.

Bleeding Disorders

World Federation of Hemophilia

Elaine Benoit of Precision BioLogic introduces the World Federation of Hemophilia, currently developing and administering their World Bleeding Disorders Registry, The WFH site is rich with authoritative bleeding disorder information and references.

Bleeding Disorders

Betrixaban (Bevyxxa) Approved June 23

The FDA approved Portola’s anti-Xa direct oral anticoagulant Betrixaban as Bevyxxa on June 23, 2017. Click or tap here for the FDA announcement and here for Portola’s press release, indications, and prescribing information. Thanks to Dr. Ali Sadeghi-Khomami of Precision BioLogic for sending along the announcement.

Comments (0)

Anticoagulant Therapy

All Posts

May We Load Syringes with Anticoagulant?

THSNA Award

Webinar: Hemostasis and Women’s Health

Mixing Studies: 4:1?

Quick Question: Specimen Storage

Quick Question: Mixing Study Results

Nijmegen Bethesda Assay

Hemorrhage Management

World Federation of Hemophilia

Betrixaban (Bevyxxa) Approved June 23

George Fritsma MS MLS

Cheat Sheets from George

Questions or Comments?

Quick Question