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Rutgers University Advanced Hemostasis Course

Thank you to Dr. Deborah Josko for her catalog description of Rutgers’ Medical Laboratory Science program CLSC 5124 Advanced Hemostasis Course, This graduate course is offered during the fall academic term for master’s and doctoral-level students. Any certified MLS/MLT professional may attend and those who are not currently matriculated into Rutgers’ graduate programs may apply […]

Plasma Collection for IVD

Thanks to Mr. Darcy Shannon of Drumlin Plasma, Inc. for the attached SOP, which distinguishes between plasma collected for IVD applications, such as coagulation calibrators, controls, and reagents, and plasma collected to produce therapeutic plasma fractions.

Bleeding Disorders

FVIII-Depleted Reagent Plasma With and Without VWF

The poster, Henneberry S, Rahman M,Wood A, Notini KM, Black KM, Sadeghi-Khomami A. Comparative analysis of commercial factor VIII (FVIII) deficient plasmas with and without von Willebrand factor for FVIII one-stage clotting assay (OSA) was presented on Thursday, 8 May 2025 at the ISLH meeting in Halifax, NS. Click here to see the poster.

Bleeding Disorders

Coagulation Specimen Management

Thanks to Tigist Bekalu for these specimen management questions… What should we do when there is lipemia, icterus (bilirubin), or hemolysis in coagulation tests? Which tests are affected and which are not? How are the results typically reported when we encounter hemolysis, icterus, or lipemia? Sometimes, instead of a number, it just says “Failed.” Also, […]

Impact of Sodium Citrate Levels on Coagulation Assays

Click here to see a poster describing the effects of varying citrate concentrations on clot-based assays: Rahman M, Bruhm M, Black KM, Sadeghi-Khomami A. Impact of sodium citrate levels in coagulation assays: A controlled ex-vivo study. Poster Presented at ISLH 2025. The findings will help us determine the effects of underfilling or overfilling blue-closure tubes […]

Specimen Management

What is NASCOLA?

I (Geo) enjoyed dining with our NASCOLA colleagues on Wednesday, 7 May 2025, while attending the 2025 ISLH annual meeting in Halifax, NS. NASCOLA is a nonprofit organization that provides proficiency testing services for North American laboratories that perform diagnostic testing for bleeding or thrombotic disorders, thereby improving performance standards. NASCOLA reviews and assists with […]

What is Abelacimab?

In 2020 we posted news about a new anticoagulant osocimab, an early and ongoing effort to develop a monoclonal antibody that neutralizes FXI and FXIa. Click here for a press release from Anthos Therapeutics (formerly Blackstone Life Sciences) describing results from the AZALEA-TIMI 71 study that was discontinued early due to an overwhelming reduction in […]

Anticoagulant Therapy

Clotpedia

Click here for Clotpedia, a new (2025) ECAT service developed by Dr. Piet Meijer. Please visit our “Resources” page at your convenience.

Global Organizations Issue Urgent Call to Action

Click here for the ISTH 6 May 2025 Call to Action: Critical Juncture in Hemophilia Treatment. Thanks to Elaine Benoit, Precision BioLogic Inc. for the heads-up. Please post your comments below. From Bob Gosselin, 7 May 2025: This link is more of a political statement than any notion of gene Rx acceptance treatment in HA […]

Bleeding Disorders

May 2025 Cheat Sheet

Here is the May 2025 Cheat Sheet with links to our April entries. Watch for your Cheat Sheet by email. The Cheat Sheet is free, you may get on the mailing list by completing the brief form on the right.

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George Fritsma is a medical laboratory scientist, educator, and author. George holds faculty appointments with Rutgers University and Michigan State University, and is a member of the International Society on Thrombosis and Hemostasis, American Association of Clinical Chemists, and American Society for Clinical Laboratory Science.

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